Lasers for the treatment of psoriasis: a systematic review.

Heidemeyer, Kristine; Kulaç, Mustafa; Sechi, Andrea; Cazzaniga, Simone; Naldi, Luigi (2023). Lasers for the treatment of psoriasis: a systematic review. Expert review of clinical immunology, 19(7), pp. 717-744. Taylor & Francis 10.1080/1744666X.2023.2205640

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INTRODUCTION

Phototherapy has been one of the first and still frequently used treatment modality for psoriasis. In the last decades, different types of lasers have been used for the treatment of psoriasis and other inflammatory skin diseases with variable success.

AREAS COVERED

Efficacy and safety of laser devices and intense pulsed light for the treatment of psoriasis. The literature search was conducted using the bibliographic databases MEDLINE, EMBASE and Cochrane. Search terms included "laser" AND "psoriasis", "IPL" AND "psoriasis", "intense pulsed light" AND "psoriasis".

EXPERT OPINION

Due to its high efficacy and safety profile 308nm Excimer laser retains its specific place in the treatment of plaque psoriasis as a first- or second-line therapy in mild disease or as an adjuvant treatment in case of partial response to systemic treatments in moderate to severe disease. Vascular lasers remain a last line therapy that can be tried in patients with recalcitrant limited plaques or nail affection. They are easy to apply and have a very good safety profile and tolerability, but the efficacy is limited. Fractional ablative lasers for application of laser assisted drug delivery appear interesting and a topic for further research. When using lasers for psoriasis, a good pre-treatment is mandatory.

Item Type:	Journal Article (Review Article)
Division/Institute:	04 Faculty of Medicine > Department of Dermatology, Urology, Rheumatology, Nephrology, Osteoporosis (DURN) > Clinic of Dermatology
UniBE Contributor:	Heidemeyer, Kristine, Kulaç, Mustafa, Cazzaniga, Simone
Subjects:	600 Technology > 610 Medicine & health
ISSN:	1744-8409
Publisher:	Taylor & Francis
Language:	English
Submitter:	Pubmed Import
Date Deposited:	21 Apr 2023 11:56
Last Modified:	06 Jul 2023 00:14
Publisher DOI:	10.1080/1744666X.2023.2205640
PubMed ID:	37079360
Uncontrolled Keywords:	difficult to treat locations excimer laser laser laser assisted drug delivery nail psoriasis phototherapy psoriasis pulsed dye laser treatment
URI:	https://boris.unibe.ch/id/eprint/181890