Shortage of iodinated contrast media: Status and possible chances - A systematic review.

Koeppel, David R; Boehm, Ingrid B (2023). Shortage of iodinated contrast media: Status and possible chances - A systematic review. European journal of radiology, 164, p. 110853. Elsevier 10.1016/j.ejrad.2023.110853

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PURPOSE

Covid-19 related lockdowns have resulted in a shortage of iodinated contrast media (ICM) in 2022. Health care providers have reacted with implementing conservation strategies to stay operational without compromising patient care. Although articles describing the implemented Interventions have been published, possible chances of the shortage have not yet been mentioned in the literature.

METHODS

We conducted a literature search in PubMed and Google Scholar, and analysed the background, interventions, and possible benefits of low-dose ICM regimens.

RESULTS

We included 22 articles dealing with "ICM shortage" for the analysis. The delivery bottlenecks in the USA and Australia led to two different countermeasures, 1. reduction of the number of contrast-enhanced image-guided examinations and 2. reduction of the (single) ICM dose. Interventions from both groups have resulted in significant reduction of ICM usage; however, group 1 has contributed more to overall ICM reduction. As benefit of the ICM reduction, we revealed an increased safety for patients at risk (e.g. hypersensitivity reactions, contrast-induced acute kidney injury, thyroid toxic effects).

CONCLUSION

The ICM shortage of 2022 has forced health care providers to implement conservation strategies to stay operational. Although there were already proposals for dose reduction before the corona pandemic and the associated supply bottlenecks, this situation led to the use of a reduced amount of contrast agent on a large scale. This presents a good opportunity to reconsider protocols and the use of contrast-enhanced imaging in general for future practice as it offers chances and advantages regarding costs, environmental impact, and patient safety.

Item Type:

Journal Article (Review Article)

Division/Institute:

04 Faculty of Medicine > Department of Radiology, Neuroradiology and Nuclear Medicine (DRNN) > Institute of Diagnostic, Interventional and Paediatric Radiology

UniBE Contributor:

Böhm, Ingrid

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1872-7727

Publisher:

Elsevier

Language:

English

Submitter:

Pubmed Import

Date Deposited:

09 May 2023 14:10

Last Modified:

04 Jun 2023 00:17

Publisher DOI:

10.1016/j.ejrad.2023.110853

PubMed ID:

37156181

Uncontrolled Keywords:

Breastfeeding women Contrast-induced acute kidney injury (CI-AKI) Hypersensitivity reactions Iodinated contrast medium Low-dose contrast-enhanced image-guided examination Shortage

BORIS DOI:

10.48350/182401

URI:

https://boris.unibe.ch/id/eprint/182401

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