Niemeyer, Samira Helena; Jovanovic, Nikola; Sezer, Sindy; Wittwer, Lucas Sébastien; Baumann, Tommy; Saads Carvalho, Thiago (2023). Dual protective effect of the association of plant extracts and fluoride against dentine erosion: In the presence and absence of salivary pellicle. PLoS ONE, 18(5), e0285931. Public Library of Science 10.1371/journal.pone.0285931
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OBJECTIVES
To verify the protective effect of plant extracts associated with fluoride against dental erosion of dentine, in the presence and absence of a salivary pellicle.
METHODS
Dentine specimens (n = 270) were randomly distributed into 9 experimental groups (n = 30/group): GT (green tea extract); BE (blueberry extract); GSE (grape seed extract); NaF (sodium fluoride); GT+NaF (green tea extract and NaF); BE+NaF (blueberry extract and NaF); GSE+NaF (grape seed extract and NaF); negative control (deionized water); and a positive control (commercialized mouthrinse containing stannous and fluoride). Each group was further divided into two subgroups (n = 15), according to the presence (P) or absence (NP) of salivary pellicle. The specimens were submitted to 10 cycles: 30 min incubation in human saliva (P) or only in humid chamber (NP), 2 min immersion in experimental solutions, 60 min of incubation in saliva (P) or not (NP), and 1 min erosive challenge. Dentine surface loss (dSL-10 and dSL-total), amount of degraded collagen (dColl) and total calcium release (CaR) were evaluated. Data were analyzed with Kruskal-Wallis, Dunn's and Mann-Whitney U tests (p>0.05).
RESULTS
Overall, the negative control presented the highest values of dSL, dColl and CaR, and the plant extracts showed different degrees of dentine protection. For the subgroup NP, GSE showed the best protection of the extracts, and the presence of fluoride generally further improved the protection for all extracts. For the subgroup P, only BE provided protection, while the presence of fluoride had no impact on dSL and dColl, but lowered CaR. The protection of the positive control was more evident on CaR than on dColl.
CONCLUSION
We can conclude that the plant extracts showed a protective effect against dentine erosion, regardless of the presence of salivary pellicle, and that the fluoride seems to improve their protection.
Item Type: |
Journal Article (Original Article) |
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Division/Institute: |
04 Faculty of Medicine > School of Dental Medicine > Department of Preventive, Restorative and Pediatric Dentistry 04 Faculty of Medicine > School of Dental Medicine |
UniBE Contributor: |
Niemeyer, Samira Helena, Jovanovic, Nikola, Baumann, Tommy, Saads Carvalho, Thiago |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
1932-6203 |
Publisher: |
Public Library of Science |
Language: |
English |
Submitter: |
Pubmed Import |
Date Deposited: |
19 May 2023 13:22 |
Last Modified: |
19 May 2023 13:29 |
Publisher DOI: |
10.1371/journal.pone.0285931 |
PubMed ID: |
37200261 |
BORIS DOI: |
10.48350/182677 |
URI: |
https://boris.unibe.ch/id/eprint/182677 |
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