Sabatini, Serena; Kaufmann, Marco; Fadda, Marta; Tancredi, Stefano; Noor, Nazihah; Van Der Linden, Bernadette W A; Cullati, Stéphane; Frank, Irene; Michel, Gisela; Harju, Erika; Luedi, Chantal; Frei, Anja; Ballouz, Tala; Menges, Dominik; Fehr, Jan; Kohler, Philipp; Kahlert, Christian R; Scheu, Victor; Ortega, Natalia; Chocano-Bedoya, Patricia; ... (2023). Factors Associated With COVID-19 Non-Vaccination in Switzerland: A Nationwide Study. International journal of public health, 68, p. 1605852. Frontiers 10.3389/ijph.2023.1605852
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Objectives: We compared socio-demographic characteristics, health-related variables, vaccination-related beliefs and attitudes, vaccination acceptance, and personality traits of individuals who vaccinated against COVID-19 and who did not vaccinate by December 2021. Methods: This cross-sectional study used data of 10,642 adult participants from the Corona Immunitas eCohort, an age-stratified random sample of the population of several cantons in Switzerland. We used multivariable logistic regression models to explore associations of vaccination status with socio-demographic, health, and behavioral factors. Results: Non-vaccinated individuals represented 12.4% of the sample. Compared to vaccinated individuals, non-vaccinated individuals were more likely to be younger, healthier, employed, have lower income, not worried about their health, have previously tested positive for SARS-CoV-2 infection, express lower vaccination acceptance, and/or report higher conscientiousness. Among non-vaccinated individuals, 19.9% and 21.3% had low confidence in the safety and effectiveness of SARS-CoV-2 vaccine, respectively. However, 29.1% and 26.7% of individuals with concerns about vaccine effectiveness and side effects at baseline, respectively vaccinated during the study period. Conclusion: In addition to known socio-demographic and health-related factors, non-vaccination was associated with concerns regarding vaccine safety and effectiveness.