O Bom Braga, Gabriela; Parrilli, Annapaola; Zboray, Robert; Bulatović, Milica; Wagner, Franca (2023). Quantitative Evaluation of the 3D Anatomy of the Human Osseous Spiral Lamina Using MicroCT. Journal of the Association for Research in Otolaryngology JARO, 24(4), pp. 441-452. Springer 10.1007/s10162-023-00904-3
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PURPOSE
The osseous spiral lamina (OSL) is an inner cochlear bony structure that projects from the modiolus from base to apex, separating the cochlear canal into the scala vestibuli and scala tympani. The porosity of the OSL has recently attracted the attention of scientists due to its potential impact on the overall sound transduction. The bony pillars between the vestibular and tympanic plates of the OSL are not always visible in conventional histopathological studies, so imaging of such structures is usually lacking or incomplete. With this pilot study, we aimed, for the first time, to anatomically demonstrate the OSL in great detail and in 3D.
METHODS
We measured width, thickness, and porosity of the human OSL by microCT using increasing nominal resolutions up to 2.5-µm voxel size. Additionally, 3D models of the individual plates at the basal and middle turns and the apex were created from the CT datasets.
RESULTS
We found a constant presence of porosity in both tympanic plate and vestibular plate from basal turn to the apex. The tympanic plate appears to be more porous than vestibular plate in the basal and middle turns, while it is less porous in the apex. Furthermore, the 3D reconstruction allowed the bony pillars that lie between the OSL plates to be observed in great detail.
CONCLUSION
By enhancing our comprehension of the OSL, we can advance our comprehension of hearing mechanisms and enhance the accuracy and effectiveness of cochlear models.
Item Type: |
Journal Article (Original Article) |
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Division/Institute: |
04 Faculty of Medicine > Department of Radiology, Neuroradiology and Nuclear Medicine (DRNN) > Institute of Diagnostic and Interventional Neuroradiology 10 Strategic Research Centers > ARTORG Center for Biomedical Engineering Research > ARTORG Center - Image Guided Therapy 10 Strategic Research Centers > ARTORG Center for Biomedical Engineering Research |
UniBE Contributor: |
O'Toole Bom Braga, Gabriela, Bulatovic, Milica, Wagner, Franca |
Subjects: |
600 Technology > 610 Medicine & health 500 Science > 570 Life sciences; biology |
ISSN: |
1525-3961 |
Publisher: |
Springer |
Language: |
English |
Submitter: |
Pubmed Import |
Date Deposited: |
06 Jul 2023 10:43 |
Last Modified: |
17 Sep 2023 00:15 |
Publisher DOI: |
10.1007/s10162-023-00904-3 |
PubMed ID: |
37407801 |
Uncontrolled Keywords: |
Bony pillars Human OSL thickness and width Osseous spiral lamina Porosity microCT |
BORIS DOI: |
10.48350/184523 |
URI: |
https://boris.unibe.ch/id/eprint/184523 |
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