Staruch, Michal; Gomez, Silvia; Rogers, Susanne; Takacs, Istvan; Kern, Thomas; Adler, Sabine; Cadosch, Dieter; Riesterer, Oliver (2024). Low-dose radiotherapy for greater trochanteric pain syndrome-a single-centre analysis. Strahlentherapie und Onkologie, 200(2), pp. 128-133. Springer 10.1007/s00066-023-02107-4
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PURPOSE
To determine predictive factors associated with a good response (GR) to and efficacy of low-dose radiotherapy (LDRT) in patients with greater trochanteric pain syndrome (GTPS).
METHODS
Patients with GTPS were irradiated on a linear accelerator with 0.5-1.0 Gy per fraction to a total dose of 3.0-4.0 Gy per series. The endpoint was subjective good response (GR) to treatment 2 months after completion of the last LDRT series, defined as complete pain relief or marked improvement assessed using the von Pannewitz score. A positive response to steroid injection (SI) was defined as pain relief of at least 7 days. Patient and treatment-related characteristics were evaluated with respect to LDRT outcomes.
RESULTS
Outcomes were assessed for 71 peritrochanteric spaces (PTSs; 65 patients, 48 females, with mean age of 63 [44-91] years). Prior SI had been given to 55 (77%) PTSs and 40 PTSs received two series of LDRT. Two months after completion of LDRT, GR was reported in 42 PTSs (59%). Two series of LDRT provided a significantly higher rate of GR than one series (72.5 vs. 42% PTSs, p = 0.015). Temporary pain relief after prior SI predicted GR to LDRT compared with PTSs which had not responded to SI (73 vs. 28% PTSs, p = 0.001). A regional structural abnormality, present in 34 PTSs (48%), was associated with a reduction of GR to LDRT (44 vs. 73% PTSs, p = 0.017).
CONCLUSION
LDRT is an effective treatment for GTPS. Administration of two LDRT series, prior response to SI, and absence of structural abnormalities may predict significantly better treatment outcomes.
Item Type: |
Journal Article (Original Article) |
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Division/Institute: |
04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Radiation Oncology |
UniBE Contributor: |
Staruch, Michal |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
1439-099X |
Publisher: |
Springer |
Language: |
English |
Submitter: |
Pubmed Import |
Date Deposited: |
16 Aug 2023 14:33 |
Last Modified: |
09 Aug 2024 15:11 |
Publisher DOI: |
10.1007/s00066-023-02107-4 |
Related URLs: |
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PubMed ID: |
37580573 |
Uncontrolled Keywords: |
Benign disease Greater trochanteric pain syndrome Low-dose radiation therapy Radiotherapy Trochanteric bursitis |
BORIS DOI: |
10.48350/185470 |
URI: |
https://boris.unibe.ch/id/eprint/185470 |
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