Can vitamins improve periodontal wound healing/regeneration?

Fawzy El-Sayed, Karim M; Cosgarea, Raluca; Sculean, Anton; Doerfer, Christof (2024). Can vitamins improve periodontal wound healing/regeneration? Periodontology 2000, 94(1), pp. 539-602. Wiley 10.1111/prd.12513

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Periodontitis is a complex inflammatory disorder of the tooth supporting structures, associated with microbial dysbiosis, and linked to a number if systemic conditions. Untreated it can result in an irreversible damage to the periodontal structures and eventually teeth loss. Regeneration of the lost periodontium requires an orchestration of a number of biological events on cellular and molecular level. In this context, a set of vitamins have been advocated, relying their beneficial physiological effects, to endorse the biological regenerative events of the periodontium on cellular and molecular levels. The aim of the present article is to elaborate on the question whether or not vitamins improve wound healing/regeneration, summarizing the current evidence from in vitro, animal and clinical studies, thereby shedding light on the knowledge gap in this field and highlighting future research needs. Although the present review demonstrates the current heterogeneity in the available evidence and knowledge gaps, findings suggest that vitamins, especially A, B, E, and CoQ10 , as well as vitamin combinations, could exert positive attributes on the periodontal outcomes in adjunct to surgical or nonsurgical periodontal therapy.

Item Type:

Journal Article (Review Article)

Division/Institute:

04 Faculty of Medicine > School of Dental Medicine > Department of Periodontology
04 Faculty of Medicine > School of Dental Medicine

UniBE Contributor:

Sculean, Anton

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1600-0757

Publisher:

Wiley

Language:

English

Submitter:

Pubmed Import

Date Deposited:

21 Aug 2023 13:10

Last Modified:

18 May 2024 00:12

Publisher DOI:

10.1111/prd.12513

PubMed ID:

37592831

Uncontrolled Keywords:

clinical healing in vitro periodontology regeneration vitamins

BORIS DOI:

10.48350/185564

URI:

https://boris.unibe.ch/id/eprint/185564

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