Factors Influencing the Course and Outcome of Early Intervention for Borderline Personality Disorder Among Adolescents

Kaess, Michael; Lerch, Stefan; Reichl, Corinna; Thomson, Madelyn Brooke; Seiffert, Nora Olivia; Koenig, Julian; Cavelti, Marialuisa (10 July 2023). Factors Influencing the Course and Outcome of Early Intervention for Borderline Personality Disorder Among Adolescents (Unpublished). In: IEPA's 14th International Conference on Early Intervention in Mental Health. Lausanne, Switzerland. 10.07.-12.07.2023.

Objectives: Since early detection and intervention in adolescent borderline personality disorder (BPD) is now state-of-the-art, research on factors that influence the course of BPD during early intervention has become critical further adapt treatment strategies and consequently improve outcomes. The present talk aims to give an overview over recent empirical findings on factors that influence outcomes within a specialized center for early intervention in BPD. Methods: Data are drawn from the AtR!Sk Cohort Study that followed adolescents (12-17 years) after receiving specialized early detection and intervention for BPD at the University Hospital Heidelberg, Germany. Overall, N=672 adolescents were included at baseline, and followed over the course of 5 years. Main outcomes for this cohort were BPD, self-harm, and psychosocial functioning. Most interesting predictors that will be presented were: Age, treatment setting, and depression. In addition, a specialized stepped-care algorithm for AtR!Sk was investigated. Results: The overall cohort showed a reduction of BPD and self-harm as well as improvement of psychosocial functioning over time. Age significantly predicted the course of BPD with older adolescents showing a steeper decline of BPD symptom. However, when modelling the course against the normative course of BPD, treatments effects become visible at each age (e.g. preventing an increase of BPD at ages 12-14 years). Adjusting for several confounders, adolescents who received inpatient treatment had a significantly worse outcome. Depressive symptoms predicted non-response and non-remission of self-harm. The overall stepped-care algorithm could be validated by the preliminary outcome data.

Item Type:

Conference or Workshop Item (Speech)

Division/Institute:

04 Faculty of Medicine > University Psychiatric Services > University Hospital of Child and Adolescent Psychiatry and Psychotherapy
04 Faculty of Medicine > University Psychiatric Services > University Hospital of Child and Adolescent Psychiatry and Psychotherapy > Research Division

UniBE Contributor:

Kaess, Michael, Lerch, Stefan, Reichl, Corinna, Thomson, Madelyn Brooke, Seiffert, Nora Olivia, Koenig, Julian, Cavelti, Marialuisa (A)

Subjects:

600 Technology > 610 Medicine & health

Language:

English

Submitter:

Chantal Michel

Date Deposited:

21 Aug 2023 11:29

Last Modified:

21 Aug 2023 11:29

URI:

https://boris.unibe.ch/id/eprint/185610

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