Benz, Dominik C; Gräni, Christoph; Antiochos, Panagiotis; Heydari, Bobak; Gissler, Mark Colin; Ge, Yin; Cuddy, Sarah A M; Dorbala, Sharmila; Kwong, Raymond Y (2023). Cardiac magnetic resonance biomarkers as surrogate endpoints in cardiovascular trials for myocardial diseases. European heart journal, 44(45), pp. 4738-4747. Oxford University Press 10.1093/eurheartj/ehad510
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Cardiac magnetic resonance offers multiple facets in the diagnosis, risk stratification, and management of patients with myocardial diseases. Particularly, its feature to precisely monitor disease activity lends itself to quantify response to novel therapeutics. This review critically appraises the value of cardiac magnetic resonance imaging biomarkers as surrogate endpoints for prospective clinical trials. The primary focus is to comprehensively outline the value of established cardiac magnetic resonance parameters in myocardial diseases. These include heart failure, cardiac amyloidosis, iron overload cardiomyopathy, hypertrophic cardiomyopathy, cardio-oncology, and inflammatory cardiomyopathies like myocarditis and sarcoidosis.
Item Type: |
Journal Article (Review Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Department of Cardiovascular Disorders (DHGE) > Clinic of Cardiology |
UniBE Contributor: |
Gräni, Christoph |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
1522-9645 |
Publisher: |
Oxford University Press |
Language: |
English |
Submitter: |
Pubmed Import |
Date Deposited: |
14 Sep 2023 08:24 |
Last Modified: |
02 Dec 2023 00:14 |
Publisher DOI: |
10.1093/eurheartj/ehad510 |
PubMed ID: |
37700499 |
Uncontrolled Keywords: |
Biomarker CMR Clinical trial Echocardiography Imaging PET |
BORIS DOI: |
10.48350/186290 |
URI: |
https://boris.unibe.ch/id/eprint/186290 |
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