Zhu, Hongcheng; Hao, Shengnan; Tseng, Ihsuan; Shen, Jingyi; Rivin Del Campo, Eleonor; Davies, Amy; Segelov, Eva; Liu, Qiufang; Chen, Yun; Song, Shaoli; Zhao, Kuaile (2023). Interim position emission tomography-computed tomography during multimodality treatment of locally advanced esophageal cancer: a scoping review. Quantitative imaging in medicine and surgery, 13(9), pp. 6280-6295. AME Publishing Company 10.21037/qims-22-1306
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BACKGROUND
Among cancers, esophageal cancer (EC) has one of the highest incidences and mortality in Asia. As recognized in many national guidelines, functional imaging performed with position emission tomography is recommended for patients with locally advanced disease. This review evaluated evidence for the use of fluorodeoxyglucose (FDG) interim positron emission tomography (PETint) in bimodality (chemoradiation) and trimodality (chemoradiation followed by surgery) management of locally advanced esophageal cancer (LAEC), with a focus on its prognostic and predictive value.
METHODS
The MEDLINE database was searched from January 1, 2001, to January 1, 2022, as part of a scoping review. References of selected articles were manually checked to identify other articles meeting the inclusion criteria; only original articles were included, and reviews, guidelines, letters, editorials, and case reports were excluded.
RESULTS
A total of 63 articles were included in this review. PET-computed tomography (PET-CT) is recognized as having a significant role in the assessment of treatment response. Studies on the predictive PETint suggest that it has a certain value, particularly for early response. Identification of poor responders or nonresponders soon after commencement of multimodality treatment allows for treatment modification.
CONCLUSIONS
The scoping review indicated variable utility for the prognostic value of PETint. There is a need to improve its accuracy, which can likely be achieved through greater standardization of measurements and reporting and testing as well as combination with other promising measures of response to residual disease.
Item Type: |
Journal Article (Review Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Radiation Oncology 04 Faculty of Medicine > Pre-clinic Human Medicine > Department of Clinical Research (DCR) |
UniBE Contributor: |
Segelov, Eva |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
2223-4292 |
Publisher: |
AME Publishing Company |
Language: |
English |
Submitter: |
Pubmed Import |
Date Deposited: |
15 Sep 2023 15:32 |
Last Modified: |
11 Jun 2024 07:37 |
Publisher DOI: |
10.21037/qims-22-1306 |
PubMed ID: |
37711778 |
Uncontrolled Keywords: |
Esophageal cancer (EC) FDG PET-CT interim prognostic value |
BORIS DOI: |
10.48350/186339 |
URI: |
https://boris.unibe.ch/id/eprint/186339 |
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