Exploration of overlap volumes for radiotherapy plan evaluation with the aim of healthy tissue sparing.

Schlachter, Matthias; Peters, Samuel; Camenisch, Daniel; Putora, Paul Martin; Bühler, Katja (2023). Exploration of overlap volumes for radiotherapy plan evaluation with the aim of healthy tissue sparing. (In Press). Computers in biology and medicine, 166(107523), p. 107523. Pergamon 10.1016/j.compbiomed.2023.107523

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PURPOSE

Development of a novel interactive visualization approach for the exploration of radiotherapy treatment plans with a focus on overlap volumes with the aim of healthy tissue sparing.

METHODS

We propose a visualization approach to include overlap volumes in the radiotherapy treatment plan evaluation process. Quantitative properties can be interactively explored to identify critical regions and used to steer the visualization for a detailed inspection of candidates. We evaluated our approach with a user study covering the individual visualizations and their interactions regarding helpfulness, comprehensibility, intuitiveness, decision-making and speed.

RESULTS

A user study with three domain experts was conducted using our software and evaluating five data sets each representing a different type of cancer and location by performing a set of tasks and filling out a questionnaire. The results show that the visualizations and interactions help to identify and evaluate overlap volumes according to their physical and dose properties. Furthermore, the task of finding dose hot spots can also benefit from our approach.

CONCLUSIONS

The results indicate the potential to enhance the current treatment plan evaluation process in terms of healthy tissue sparing.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Radiation Oncology

UniBE Contributor:

Putora, Paul Martin

Subjects:

600 Technology > 610 Medicine & health

ISSN:

0010-4825

Publisher:

Pergamon

Language:

English

Submitter:

Pubmed Import

Date Deposited:

03 Oct 2023 15:53

Last Modified:

04 Oct 2023 16:54

Publisher DOI:

10.1016/j.compbiomed.2023.107523

PubMed ID:

37778212

Uncontrolled Keywords:

Healthy tissue sparing Overlap volume Radiotherapy planning Visual computing Visualization

BORIS DOI:

10.48350/186849

URI:

https://boris.unibe.ch/id/eprint/186849

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