Tolstik, Elen; Lehnart, Stephan E; Soeller, Christian; Lorenz, Kristina; Sacconi, Leonardo (2024). Cardiac multiscale bioimaging: from nano- through micro- to mesoscales. Trends in Biotechnology, 42(2), pp. 212-227. Elsevier 10.1016/j.tibtech.2023.08.007
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Cardiac multiscale bioimaging is an emerging field that aims to provide a comprehensive understanding of the heart and its functions at various levels, from the molecular to the entire organ. It combines both physiologically and clinically relevant dimensions: from nano- and micrometer resolution imaging based on vibrational spectroscopy and high-resolution microscopy to assess molecular processes in cardiac cells and myocardial tissue, to mesoscale structural investigations to improve the understanding of cardiac (patho)physiology. Tailored super-resolution deep microscopy with advanced proteomic methods and hands-on experience are thus strategically combined to improve the quality of cardiovascular research and support future medical decision-making by gaining additional biomolecular information for translational and diagnostic applications.
Item Type: |
Journal Article (Review Article) |
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Division/Institute: |
04 Faculty of Medicine > Pre-clinic Human Medicine > Institute of Physiology |
UniBE Contributor: |
Soeller, Johannes Christian |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
1879-3096 |
Publisher: |
Elsevier |
Language: |
English |
Submitter: |
Pubmed Import |
Date Deposited: |
09 Oct 2023 12:46 |
Last Modified: |
10 Feb 2024 00:13 |
Publisher DOI: |
10.1016/j.tibtech.2023.08.007 |
PubMed ID: |
37806897 |
Uncontrolled Keywords: |
cardiac imaging electron tomography mesoscale cardiac imaging optogenetics super-resolution microscopy vibrational spectroscopy |
BORIS DOI: |
10.48350/186986 |
URI: |
https://boris.unibe.ch/id/eprint/186986 |
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