Princip, Mary; von Känel, Roland; Sivakumar, Sinthujan; Jellestad, Lena; Pazhenkottil, Aju P; Langraf-Meister, Rebecca E; Znoj, Hansjörg; Schmid, Jean-Paul; Barth, Jürgen; Schnyder, Ulrich; Zuccarella-Hackl, Claudia (2023). Longitudinal association between positive affect and blood lipids in patients following acute myocardial infarction. PLoS ONE, 18(11), e0287166. Public Library of Science 10.1371/journal.pone.0287166
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OBJECTIVE
Unfavorable blood lipid profiles are robust risk factors in predicting atherosclerotic disease. Studies have shown that positive affect (PA) is associated with a favorable lipid profile. However, longitudinal studies regarding the course of PA and lipid profiles in myocardial infarction (MI) patients are lacking. Therefore, the aim of this study was to prospectively explore the association between PA and blood lipid levels across three inv estigations over 12 months following acute MI.
METHODS
Patients following an acute MI were examined at hospital admission (n = 190), and at 3 months (n = 154) and 12 months (n = 106) thereafter. Linear mixed effect regression models were used to evaluate the relation between PA, assessed with the Global Mood Scale, and blood lipid levels. Potential confounding variables were controlled for in the analysis.
RESULTS
Higher PA was significantly associated with higher high-density lipoprotein cholesterol (HDL-C) levels and a lower total cholesterol (TC)/HDL-C ratio over time, independent of demographic factors, indices of cardiac disease severity, comorbidity, medication use, health behaviors, serum cortisol and negative affect (p≤0.040). No association was found between PA and the two blood lipids low-density lipoprotein-cholesterol (LDL-C) and triglycerides (TG).
CONCLUSIONS
Positive affect was independently associated with HDL-C levels and the TC/HDL-C ratio in patients up to 1 year after MI. The findings support a potential role of PA for cardiovascular health through an association with a favorable blood lipid profile.
Item Type: |
Journal Article (Original Article) |
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Division/Institute: |
07 Faculty of Human Sciences > Institute of Psychology > Clinical Psychology and Psychotherapy 07 Faculty of Human Sciences > Institute of Psychology 07 Faculty of Human Sciences > Institute of Psychology > Psychological and Behavioral Health |
UniBE Contributor: |
Znoj, Hans Jörg |
Subjects: |
100 Philosophy > 150 Psychology 600 Technology > 610 Medicine & health 200 Religion > 250 Christian pastoral practice & religious orders |
ISSN: |
1932-6203 |
Publisher: |
Public Library of Science |
Language: |
English |
Submitter: |
Pubmed Import |
Date Deposited: |
03 Nov 2023 14:00 |
Last Modified: |
12 Nov 2023 02:34 |
Publisher DOI: |
10.1371/journal.pone.0287166 |
PubMed ID: |
37917632 |
BORIS DOI: |
10.48350/188539 |
URI: |
https://boris.unibe.ch/id/eprint/188539 |
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