Multilineage circuits of regenerative cell states.

Gote-Schniering, Janine; Schiller, Herbert B (2023). Multilineage circuits of regenerative cell states. Cell stem cell, 30(11), pp. 1397-1399. Elsevier 10.1016/j.stem.2023.10.006

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Regenerating the lungs' architecture after injury requires rebuilding its fibroelastic extracellular matrix scaffold. Konkimalla et al. establish that regenerative cell states (RCSs) of both epithelial and mesenchymal origin are functionally linked and indispensable for this process. Experimental ablation of RCSs causes organ degeneration, whereas their induction causes organ fibrosis.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Dermatology, Urology, Rheumatology, Nephrology, Osteoporosis (DURN) > Clinic of Rheumatology, Clinical Immunology and Allergology

UniBE Contributor:

Gote-Schniering, Janine

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1934-5909

Publisher:

Elsevier

Language:

English

Submitter:

Pubmed Import

Date Deposited:

06 Nov 2023 12:19

Last Modified:

07 Nov 2023 03:52

Publisher DOI:

10.1016/j.stem.2023.10.006

PubMed ID:

37922876

BORIS DOI:

10.48350/188602

URI:

https://boris.unibe.ch/id/eprint/188602

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