[Treatment of uveitis-associated refractory ocular hypotony with topical ibopamine]

Windisch, B K; Iliev, M E (2006). [Treatment of uveitis-associated refractory ocular hypotony with topical ibopamine]. Klinische Monatsblätter für Augenheilkunde, 223(5), pp. 422-4. Stuttgart: Ferdinand Enke Verlag 10.1055/s-2006-926574

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BACKGROUND: Ibopamine is a non-selective dopamine- and adrenalin-receptor agonist that has been shown to cause pupillary dilation and an increase in aqueous humour secretion. This novel drug can be used as a mydriatic agent, as a provocative test in open-angle glaucoma, and for the treatment of persisting ocular hypotony. HISTORY AND SIGNS: This 47-year-old man had a history of uveitis associated with Crohn's disease. Six years after deep sclerectomy for uveitic secondary glaucoma, he developed severe hypotony in his left eye with drop of visual acuity (VA). The hypotony did not respond to topical steroid treatment. 2 % Ibopamine solution was ordered t. i. d. concomitant to 1 % prednisolone acetate. THERAPY AND OUTCOME: Intraocular pressure (IOP) began to rise after 3 weeks of Ibopamine treatment and returned to normal (12 mmHg) with continuous recovery of VA after 8 weeks. Ibopamine was discontinued at an IOP of 16 mmHg after a course of 12 weeks. IOP and VA remained stable during the 12-month follow-up period. CONCLUSIONS: Ibopamine 2 % eye drops in combination with topical steroids are a therapeutic option in uveitis-associated ocular hypotony.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Ophthalmology

UniBE Contributor:

Windisch, Bettina Katrin and Iliev, Milko Emilov

ISSN:

0023-2165

ISBN:

16705521

Publisher:

Ferdinand Enke Verlag

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:45

Last Modified:

04 May 2014 23:13

Publisher DOI:

10.1055/s-2006-926574

PubMed ID:

16705521

Web of Science ID:

000238027900022

URI:

https://boris.unibe.ch/id/eprint/18869 (FactScience: 1123)

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