Berdan, Emma L; Barton, Nicholas H; Butlin, Roger; Charlesworth, Brian; Faria, Rui; Fragata, Inês; Gilbert, Kimberly J; Jay, Paul; Kapun, Martin; Lotterhos, Katie E; Mérot, Claire; Durmaz Mitchell, Esra; Pascual, Marta; Peichel, Catherine L; Rafajlović, Marina; Westram, Anja M; Schaeffer, Stephen W; Johannesson, Kerstin; Flatt, Thomas (2023). How chromosomal inversions reorient the evolutionary process. Journal of evolutionary biology, 36(12), pp. 1761-1782. Wiley 10.1111/jeb.14242
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J_of_Evolutionary_Biology_-_2023_-_Berdan_-_How_chromosomal_inversions_reorient_the_evolutionary_process.pdf - Published Version Available under License Creative Commons: Attribution-Noncommercial (CC-BY-NC). Download (1MB) | Preview |
Inversions are structural mutations that reverse the sequence of a chromosome segment and reduce the effective rate of recombination in the heterozygous state. They play a major role in adaptation, as well as in other evolutionary processes such as speciation. Although inversions have been studied since the 1920s, they remain difficult to investigate because the reduced recombination conferred by them strengthens the effects of drift and hitchhiking, which in turn can obscure signatures of selection. Nonetheless, numerous inversions have been found to be under selection. Given recent advances in population genetic theory and empirical study, here we review how different mechanisms of selection affect the evolution of inversions. A key difference between inversions and other mutations, such as single nucleotide variants, is that the fitness of an inversion may be affected by a larger number of frequently interacting processes. This considerably complicates the analysis of the causes underlying the evolution of inversions. We discuss the extent to which these mechanisms can be disentangled, and by which approach.
Item Type: |
Journal Article (Review Article) |
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Division/Institute: |
08 Faculty of Science > Department of Biology > Institute of Ecology and Evolution (IEE) > Evolutionary Ecology 08 Faculty of Science > Department of Biology > Institute of Ecology and Evolution (IEE) |
UniBE Contributor: |
Peichel, Catherine |
Subjects: |
500 Science > 570 Life sciences; biology |
ISSN: |
1420-9101 |
Publisher: |
Wiley |
Language: |
English |
Submitter: |
Pubmed Import |
Date Deposited: |
13 Nov 2023 16:39 |
Last Modified: |
21 Dec 2023 00:15 |
Publisher DOI: |
10.1111/jeb.14242 |
PubMed ID: |
37942504 |
Uncontrolled Keywords: |
adaptation balanced polymorphisms chromosomal rearrangements inversions linkage neutrality recombination selection |
BORIS DOI: |
10.48350/188754 |
URI: |
https://boris.unibe.ch/id/eprint/188754 |
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