Identification of novel targets for immunotherapies in subsets of patients with diffuse large B-cell lymphoma (DLBCL).

Heini, Alexander D; Bacher, Ulrike; Pabst, Thomas (2024). Identification of novel targets for immunotherapies in subsets of patients with diffuse large B-cell lymphoma (DLBCL). British journal of haematology, 204(2), pp. 389-390. Wiley-Blackwell 10.1111/bjh.19195

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Personalized treatment options for subsets of patients with DLBCL are beginning to emerge. Caracciolo et al. explore UMG1, an epitope of CD43 as a potential target for certain patients with DLBCL, and demonstrate promising preclinical activity of an Anti-UMG1-antibody. Commentary on: Caracciolo et al. UMG1/CD3ε-bispecific T-cell engager (BTCE) redirects T-cell cytotoxicity against diffuse large B-cell lymphoma (DLBCL). Br J Haematol 2023 (Online ahead of print). doi: 10.1111/bjh.19183.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Medical Oncology
04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Haematology and Central Haematological Laboratory

UniBE Contributor:

Heini, Alexander, Bacher, Vera Ulrike, Pabst, Thomas Niklaus

Subjects:

600 Technology > 610 Medicine & health

ISSN:

0007-1048

Publisher:

Wiley-Blackwell

Language:

English

Submitter:

Pubmed Import

Date Deposited:

16 Nov 2023 14:11

Last Modified:

08 Feb 2024 00:13

Publisher DOI:

10.1111/bjh.19195

PubMed ID:

37964473

Uncontrolled Keywords:

DLBCL UMG1 bispecific T-cell engager personalized medicine

BORIS DOI:

10.48350/188945

URI:

https://boris.unibe.ch/id/eprint/188945

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