Increasing insight in the value of repetitive COVID-19 vaccination in patients with haematological malignancies in the Omicron era.

Bacher, Vera; Shumilov, Evgenii; Pabst, Thomas (2024). Increasing insight in the value of repetitive COVID-19 vaccination in patients with haematological malignancies in the Omicron era. British journal of haematology, 204(2), pp. 386-388. Wiley 10.1111/bjh.19221

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The study by Kevlicius et al. from Lithuania gives further confirmation of the efficacy of booster mRNA COVID-19 vaccination for patients with haemato-oncological malignancies in the Omicron era. The risk of COVID-19 and mortality was considerably reduced when patients received the booster vaccination. The threshold of the humoral response to vaccination that was protective for haemato-oncological patients was defined. In particular, ruxolitinib and anti-CD20 treatments limited the humoral response to the third booster vaccination. These data may influence the clinical management of haemato-oncological patients in future waves of the COVID-19 pandemic, regarding for example the selection of patients for passive immunization against SARS-CoV-2. Commentary on: Kevličius et al. Immunogenicity and clinical effectiveness of mRNA vaccine booster against SARS-CoV-2 Omicron in patients with haematological malignancies: A national prospective cohort study. Br J Haematol 2023 (Online ahead of print). doi: 10.1111/bjh.19126.

Item Type:

Journal Article (Further Contribution)

Division/Institute:

04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Haematology and Central Haematological Laboratory
04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Medical Oncology

UniBE Contributor:

Bacher, Vera Ulrike, Pabst, Thomas Niklaus

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1365-2141

Publisher:

Wiley

Language:

English

Submitter:

Pubmed Import

Date Deposited:

22 Nov 2023 10:16

Last Modified:

08 Feb 2024 00:14

Publisher DOI:

10.1111/bjh.19221

PubMed ID:

37984996

Uncontrolled Keywords:

Omicron haematologic malignancies repetitive COVID-19 vaccination

BORIS DOI:

10.48350/189245

URI:

https://boris.unibe.ch/id/eprint/189245

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