Practice Patterns in Fournier's Gangrene in Europe and Implications for a Prospective Registry Study.

Schneidewind, Laila; Kiss, Bernhard; Stangl, Fabian P.; Tandogdu, Zafer; Wagenlehner, Florian M E; Johansen, Truls E Bjerklund; Köves, Béla; Medina-Polo, Jose; Tapia, Ana Maria; Kranz, Jennifer (2023). Practice Patterns in Fournier's Gangrene in Europe and Implications for a Prospective Registry Study. Antibiotics, 12(2) MDPI 10.3390/antibiotics12020197

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BACKGROUND

Fournier's gangrene (FG) is a life-threatening, necrotizing infection. Due to the rareness of the disease, it is challenging to plan robust prospective studies. This study aims to describe current practice patterns of FG in Europe and identify implications for planning a prospective FG registry.

METHODS

Online non-validated 17-items survey among urologists treating FG in in European hospitals. Questionnaires were analyzed with LimeSurvey (LimeSurvey GmbH Hamburg, Germany).

RESULTS

229 responses from ten different European countries were submitted, and 117 (51.1%) urologists completed the questionnaire. The departments treat a mean of 4.2 (SD 3.11) patients per year. The urology department mostly takes the lead in treating FG patients (n = 113; 96.6%). The practice in FG is very heterogenic and mostly case-based all over Europe, e.g., vacuum-assisted wound closure (VAC) is mostly used (n = 50; 42.7%) as adjunct wound. The biggest challenges in FG are the short time to diagnosis and treatment, standardization and establishment of guidelines, and disease awareness. Additionally, participants stated that an international registry is an outstanding initiative, and predictive models are needed.

CONCLUSIONS

There is no standard of care in the diagnosis, treatment, and long-term care of FG all over Europe. Further research could be conducted with a prospective registry.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Dermatology, Urology, Rheumatology, Nephrology, Osteoporosis (DURN) > Clinic of Urology

UniBE Contributor:

Kiss, Bernhard, Stangl, Fabian Peter

Subjects:

600 Technology > 610 Medicine & health

ISSN:

2079-6382

Publisher:

MDPI

Language:

English

Submitter:

Khiem Duong

Date Deposited:

22 Nov 2023 15:31

Last Modified:

22 Nov 2023 15:31

Publisher DOI:

10.3390/antibiotics12020197

PubMed ID:

36830108

Uncontrolled Keywords:

Fournier’s gangrene antibiotic stewardship necrotizing fasciitis outcome parameters sepsis

BORIS DOI:

10.48350/189268

URI:

https://boris.unibe.ch/id/eprint/189268

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