Post-mortem angiography after vascular perfusion with diesel oil and a lipophilic contrast agent

Grabherr, Silke; Djonov, Valentin; Friess, Armin; Thali, Michael J; Ranner, Gerhard; Vock, Peter; Dirnhofer, Richard (2006). Post-mortem angiography after vascular perfusion with diesel oil and a lipophilic contrast agent. AJR, American journal of roentgenology, 187(5), W515-23. Leesburg, Va.: American Roentgen Ray Society

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OBJECTIVE: The objective of our study was to establish optimal perfusion conditions for high-resolution postmortem angiography that would permit dynamic visualization of the arterial and venous systems. MATERIALS AND METHODS: Cadavers of two dogs and one cat were perfused with diesel oil through a peristaltic pump. The lipophilic contrast agent Lipiodol Ultra Fluide was then injected, and angiography was performed. The efficiency of perfusion was evaluated in the chick chorioallantoic membrane. RESULTS: Vessels could be seen up to the level of the smaller supplying and draining vessels. Hence, both the arterial and the venous sides of the vascular system could be distinguished. The chorioallantoic membrane assay revealed that diesel oil enters microvessels up to 50 microm in diameter and that it does not penetrate the capillary network. CONCLUSION: After establishing a postmortem circulation by diesel oil perfusion, angiography can be performed by injection of Lipiodol Ultra Fluide. The resolution of the images obtained up to 3 days after death is comparable to that achieved in clinical angiography.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Service Sector > Institute of Legal Medicine
04 Faculty of Medicine > Pre-clinic Human Medicine > Institute of Anatomy
04 Faculty of Medicine > Department of Radiology, Neuroradiology and Nuclear Medicine (DRNN) > Institute of Diagnostic, Interventional and Paediatric Radiology

UniBE Contributor:

Grabherr, Silke Doris; Djonov, Valentin; Thali, Michael and Vock, Peter

ISSN:

0361-803X

ISBN:

17056884

Publisher:

American Roentgen Ray Society

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:46

Last Modified:

04 May 2014 23:13

PubMed ID:

17056884

URI:

https://boris.unibe.ch/id/eprint/18934 (FactScience: 1205)

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