Prevention of Oncogenic Gammaherpesvirinae (EBV and HHV8) Associated Disease in Solid Organ Transplant Recipients.

Atamna, Alaa; Yahav, Dafna; Hirzel, Cédric (2023). Prevention of Oncogenic Gammaherpesvirinae (EBV and HHV8) Associated Disease in Solid Organ Transplant Recipients. Transplant international, 36(11856), p. 11856. Wiley 10.3389/ti.2023.11856

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Long-term risk for malignancy is higher among solid organ transplant (SOT) recipients compared to the general population. Four non-hepatitis viruses have been recognized as oncogenic in SOT recipients-EBV, cause of EBV-associated lymphoproliferative diseases; human herpes virus 8 (HHV8), cause of Kaposi sarcoma, primary effusion lymphoma and multicentric Castleman disease; human papilloma virus, cause of squamous cell skin cancers, and Merkel cell polyomavirus, cause of Merkel cell carcinoma. Two of these viruses (EBV and HHV8) belong to the human herpes virus family. In this review, we will discuss key aspects regarding the clinical presentation, diagnosis, treatment, and prevention of diseases in SOT recipients associated with the two herpesviruses.

Item Type:

Journal Article (Review Article)

Division/Institute:

04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Infectiology

UniBE Contributor:

Hirzel, Cédric

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1432-2277

Publisher:

Wiley

Language:

English

Submitter:

Pubmed Import

Date Deposited:

06 Dec 2023 15:15

Last Modified:

10 Dec 2023 02:30

Publisher DOI:

10.3389/ti.2023.11856

PubMed ID:

38046068

Uncontrolled Keywords:

Epstein-Barr virus Kaposi sarcoma human herpes virus 8 multicentic Castleman disease posttransplant lymphoproliferative disorders primary effusion lymphoma

BORIS DOI:

10.48350/189815

URI:

https://boris.unibe.ch/id/eprint/189815

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