Isler, Sila Cagri; Bellon, Benjamin; Foss, Morten; Pippenger, Benjamin; Stavropoulos, Andreas; Ole Zoffmann, Andersen (2024). Assessing the osseointegration potential of a strontium releasing nanostructured titanium oxide surface: A biomechanical study in the rabbit tibia plateau model. Clinical and experimental dental research, 10(1), e812. Wiley 10.1002/cre2.812
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Clinical___Exp_Dental_Res_-_2023_-_Isler_-_Assessing_the_osseointegration_potential_of_a_strontium_releasing_nanostructured.pdf - Published Version Available under License Creative Commons: Attribution (CC-BY). Download (1MB) | Preview |
OBJECTIVES
To investigate the impact of a Ti-Sr-O technology, applied to either a turned surface or an SLA surface, on the mechanical robustness of osseointegration, benchmarked against the SLActive surface.
MATERIAL AND METHODS
Ti discs (6.25-mm-diameter and 2-mm-thick) with three different surfaces were inserted on the proximal-anterior part of the tibial plateau of adult Swedish loop rabbits: (I) turned surface modified with Ti-Sr-O (turned + Ti-Sr-O), (II) SLA surface modified with Ti-Sr-O (SLA + Ti-Sr-O), and (III) SLActive surface (SLActive). Following a healing period of 2 weeks and 4 weeks, the pull-out (PO) force needed to detach the discs from the bone was assessed, as a surrogate of osseointegration.
RESULTS
The SLActive surface exhibited statistically significant higher median PO forces, compared with the SLA + Ti-Sr-O surfaces at both 2- and 4 weeks post-op (p > .05). In this study, no single turned + Ti-Sr-O surface disk was integrated.
CONCLUSIONS
The tested Ti-Sr-O technology failed to enhance osseointegration; however, this finding may be related to the inappropriateness of the rabbit tibia plateau model for assessing third-generation implant surface technologies, due to the limited diffusion and clearance at the disk-bone interface.
Item Type: |
Journal Article (Original Article) |
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Division/Institute: |
04 Faculty of Medicine > School of Dental Medicine > Department of Periodontology 04 Faculty of Medicine > School of Dental Medicine 04 Faculty of Medicine > School of Dental Medicine > Periodontics Research |
UniBE Contributor: |
Isler, Sila Cagri, Pippenger, Benjamin Evans, Stavropoulos, Andreas, Ole-Zoffmann, Andersen |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
2057-4347 |
Publisher: |
Wiley |
Language: |
English |
Submitter: |
Pubmed Import |
Date Deposited: |
05 Dec 2023 10:30 |
Last Modified: |
13 Feb 2024 00:14 |
Publisher DOI: |
10.1002/cre2.812 |
PubMed ID: |
38044566 |
Uncontrolled Keywords: |
SLA Strontium osseointegration preclinical in vivo |
BORIS DOI: |
10.48350/189820 |
URI: |
https://boris.unibe.ch/id/eprint/189820 |
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