Contemporary Approach of Tricuspid Regurgitation: Knowns, Unknowns and Future Challenges.

Samim, Daryoush; Dernektsi, Chrisoula; Brugger, Nicolas; Reineke, David; Praz, Fabien (2024). Contemporary Approach of Tricuspid Regurgitation: Knowns, Unknowns and Future Challenges. The Canadian journal of cardiology, 40(2), pp. 185-200. Elsevier 10.1016/j.cjca.2023.11.041

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Severe tricuspid regurgitation (TR) worsens heart failure and is associated with impaired survival. In daily clinical practice, patients are referred late and tricuspid valve (TV) interventions (surgical or transcatheter) are underutilized, which leads to irreversible right ventricular (RV) damage and increases the risk. This article addresses the appropriate timing and modality for an intervention (surgical or transcatheter), and its potential benefits on clinical outcomes. Ongoing randomized controlled trials will provide further insights into the efficacy of transcatheter valve interventions compared to medical treatment.

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