In the human urothelium and suburothelium, intradetrusor botulinum neurotoxin type A does not induce apoptosis: preliminary results

Kessler, Thomas M; Khan, Shahid; Panicker, Jalesh N; Elneil, Sohier; Brandner, Sebastian; Fowler, Clare J; Roosen, Alexander (2010). In the human urothelium and suburothelium, intradetrusor botulinum neurotoxin type A does not induce apoptosis: preliminary results. European urology, 57(5), pp. 879-83. Amsterdam: Elsevier 10.1016/j.eururo.2009.09.023

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Intradetrusor injections of botulinum neurotoxin type A (BoNTA) are emerging as the preferred second-line treatment for neurogenic and idiopathic overactive bladder (OAB). In animal experiments, intradetrusor BoNTA injections have been shown to cause apoptosis in the bladder urothelium and suburothelium but not the detrusor.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Dermatology, Urology, Rheumatology, Nephrology, Osteoporosis (DURN) > Clinic of Urology

UniBE Contributor:

Kessler, Thomas M.

ISSN:

0302-2838

Publisher:

Elsevier

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:07

Last Modified:

04 May 2014 23:04

Publisher DOI:

10.1016/j.eururo.2009.09.023

PubMed ID:

19765885

Web of Science ID:

000275739600027

URI:

https://boris.unibe.ch/id/eprint/190 (FactScience: 196743)

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