ENLIGHT: A consensus checklist for reporting laboratory-based studies on the non-visual effects of light in humans

Spitschan, Manuel; Kervezee, Laura; Lok, Renske; McGlashan, Elise; Najjar, Raymond P. (2023). ENLIGHT: A consensus checklist for reporting laboratory-based studies on the non-visual effects of light in humans. EBioMedicine, 98, p. 104889. Elsevier 10.1016/j.ebiom.2023.104889

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Background: There is no consensus on reporting light characteristics in studies investigating non-visual responses to light. This project aimed to develop a reporting checklist for laboratory-based investigations on the impact of light on non-visual physiology.

Methods: A four-step modified Delphi process (three questionnaire-based feedback rounds and one face-to-face group discussion) involving international experts was conducted to reach consensus on the items to be included in the checklist. Following the consensus process, the resulting checklist was tested in a pilot phase with independent experts.

Findings: An initial list of 61 items related to reporting light-based interventions was condensed to a final checklist containing 25 items, based upon consensus among experts (final n = 60). Nine items were deemed necessary to report regardless of research question or context. A description of each item is provided in the accompanying Explanation and Elaboration (E&E) document. The independent pilot testing phase led to minor textual clarifications in the checklist and E&E document.

Interpretation: The ENLIGHT Checklist is the first consensus-based checklist for documenting and reporting ocular light-based interventions for human studies. The implementation of the checklist will enhance the impact of light-based research by ensuring comprehensive documentation, enhancing reproducibility, and enabling data aggregation across studies.

Item Type:

Journal Article (Review Article)

Division/Institute:

04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Ophthalmology

Subjects:

600 Technology > 610 Medicine & health

ISSN:

2352-3964

Publisher:

Elsevier

Language:

English

Submitter:

Ludovic Stéphane Mure

Date Deposited:

20 Dec 2023 10:53

Last Modified:

14 Jan 2024 02:42

Publisher DOI:

10.1016/j.ebiom.2023.104889

PubMed ID:

38043137

Additional Information:

ENLIGHT Consortium: Mure, Ludovic Stéphane

Uncontrolled Keywords:

Circadian rhythms; Interventions; Light; Non-visual effects of light; Reporting guidelines; Sleep.

BORIS DOI:

10.48350/190479

URI:

https://boris.unibe.ch/id/eprint/190479

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