Lautenschlager, Severin A; Barry, Mamadou Pathé; Rogler, Gerhard; Biedermann, Luc; Schreiner, Philipp; Siebenhüner, Alexander R (2023). Lifestyle factors associated with inflammatory bowel disease: data from the Swiss IBD cohort study. BMC gastroenterology, 23(1), p. 71. BioMed Central 10.1186/s12876-023-02692-9
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BACKGROUND
Various environmental risk factors have been associated with the pathogenesis of inflammatory bowel disease. In this study we aimed to identify lifestyle factors that affect the onset of Crohn's disease and ulcerative colitis.
METHODS
2294 patients from the Swiss IBD Cohort Study received a questionnaire regarding physical activity, nutritional habits and status of weight. In addition, a control group was formed comprising patients' childhood friends, who grew up in a similar environment.
RESULTS
Overall, 1111 questionnaires were returned (response rate: 48.4%). Significantly more patients with inflammatory bowel disease reported no regular practice of sport during childhood and beginning of adulthood compared to the control group (p = 0.0001). No association between intake of refined sugar and onset of inflammatory bowel disease was observed. More patients with Crohn's disease compared to ulcerative colitis and controls suffered from overweight during childhood (12.8% vs. 7.7% and 9.7%, respectively; p = 0.027).
CONCLUSIONS
Our study underlines the relevance of environmental factors in the development of inflammatory bowel disease. Our results imply a protective effect of physical activity regarding the onset of inflammatory bowel disease.
Item Type: |
Journal Article (Original Article) |
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Division/Institute: |
04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Visceral Surgery and Medicine > Gastroenterology 04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Visceral Surgery and Medicine |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
1471-230X |
Publisher: |
BioMed Central |
Language: |
English |
Submitter: |
Rahel Fuhrer |
Date Deposited: |
08 Jan 2024 10:39 |
Last Modified: |
08 Jan 2024 10:39 |
Publisher DOI: |
10.1186/s12876-023-02692-9 |
PubMed ID: |
36907848 |
Additional Information: |
Lukas Brügger, Ove Carstens, Benjamin Heimgartner, Pascal Juillerat, Andrew Macpherson, Benjamin Misselwitz and Reiner Wiest are member of the Swiss IBD Cohort Study Group |
Uncontrolled Keywords: |
Environmental factors Inflammatory bowel disease Nutrition Physical activity Swiss IBD cohort study |
BORIS DOI: |
10.48350/191303 |
URI: |
https://boris.unibe.ch/id/eprint/191303 |
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