Influence and predictive value of optional parameters in new-generation intraocular lens formulas

Wendelstein, Jascha A.; Rothbächer, Jan; Heath, Michael; McDonald, Michael C.; Hoffmann, Peter C.; Cooke, David L.; Seiler, Theo G.; Langenbucher, Achim; Riaz, Kamran M. (2023). Influence and predictive value of optional parameters in new-generation intraocular lens formulas. Journal of cataract and refractive surgery, 49(8), pp. 795-803. Wolters Kluwer Health 10.1097/j.jcrs.0000000000001207

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Purpose: To evaluate the accuracy of various variations of new-generation multivariate intraocular lens (IOL) power calculation using the Barrett Universal II, Castrop, Emmetropia Verifying Optical 2.0, Hill-Radial Basis Function 3.0, Kane, and PEARL-DGS formulas with and without optional biometric parameters.

Setting: Tertiary care academic medical center.

Design: Retrospective case series. Single-center study.

Methods: Inclusion of patients after uneventful cataract surgery implanting AU00T0 IOLs. Data from one eye per patient were randomly included. Eyes with a corrected distance visual acuity worse than 0.1 logMAR were excluded. IOLCON-optimized constants were used for all formulas other than the Castrop formula. The outcome measures were prediction error (PE) and absolute prediction error (absPE) for the 6 study formulas.

Results: 251 eyes from 251 patients were assessed. Excluding lens thickness led to statistically significant differences in absPE in several formulas. Leaving out horizontal corneal diameter did not impact absPE in several formulas. Differences in PE offset were observed between the various formula variations.

Conclusions: When using multivariate formulas with an A-constant, including certain optional parameters is vital for optimal refractive results. Formula variations excluding certain biometric parameters need specifically optimized constants and do not perform similarly when using the constant of the respective formula using all parameters.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Ophthalmology

UniBE Contributor:

Seiler, Günter Theodor Michael

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1873-4502

Publisher:

Wolters Kluwer Health

Language:

English

Submitter:

Demetra Olariu

Date Deposited:

09 Jan 2024 10:08

Last Modified:

09 Jan 2024 10:16

Publisher DOI:

10.1097/j.jcrs.0000000000001207

PubMed ID:

37097284

BORIS DOI:

10.48350/191361

URI:

https://boris.unibe.ch/id/eprint/191361

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