Buser, Daniel; Urban, Istvan; Monje, Alberto; Kunrath, Marcel F; Dahlin, Christer (2023). Guided bone regeneration in implant dentistry: Basic principle, progress over 35 years, and recent research activities. Periodontology 2000, 93(1), pp. 9-25. Blackwell 10.1111/prd.12539
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Bone augmentation procedures are frequent today in implant patients, since an implant should be circumferentially anchored in bone at completion of bone healing to have a good long-term stability. The best documented surgical technique to achieve this goal is guided bone regeneration (GBR) utilizing barrier membranes in combination with bone fillers. This clinical review paper reflects 35 years of development and progress with GBR. In the 1990s, GBR was developed by defining the indications for GBR, examining various barrier membranes, bone grafts, and bone substitutes. Complications were identified and reduced by modifications of the surgical technique. Today, the selection criteria for various surgical approaches are much better understood, in particular, in post-extraction implant placement. In the majority of patients, biodegradable collagen membranes are used, mainly for horizontal bone augmentation, whereas bioinert PTFE membranes are preferred for vertical ridge augmentation. The leading surgeons are using a composite graft with autogenous bone chips to accelerate bone formation, in combination with a low-substitution bone filer to better maintain the augmented bone volume over time. In addition, major efforts have been made since the millenium change to reduce surgical trauma and patient morbidity as much as possible. At the end, some open questions related to GBR are discussed.
Item Type: |
Journal Article (Review Article) |
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Division/Institute: |
04 Faculty of Medicine > School of Dental Medicine > Department of Periodontology 04 Faculty of Medicine > School of Dental Medicine > Department of Oral Surgery and Stomatology |
UniBE Contributor: |
Buser, Daniel Albin, Monje, Alberto |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
0906-6713 |
Publisher: |
Blackwell |
Language: |
English |
Submitter: |
Pubmed Import |
Date Deposited: |
10 Jan 2024 15:11 |
Last Modified: |
11 Jan 2024 17:18 |
Publisher DOI: |
10.1111/prd.12539 |
PubMed ID: |
38194351 |
Uncontrolled Keywords: |
GBR barrier membrane bone augmentation bone filler bone graft bone substitute complications selection criteria |
BORIS DOI: |
10.48350/191419 |
URI: |
https://boris.unibe.ch/id/eprint/191419 |