COVID-19 Vaccine Acceptance Among Parents of Children With Multisystem Inflammatory Syndrome in Children.

Blanchard-Rohner, Geraldine; Sanchez, Carlos; Andre, Maya C; Bressieux-Degueldre, Sabrina; Grazioli, Serge; Perez, Marie-Helene; Wütz, Daniela; Schöbi, Nina; Welzel, Tatjana; Atkinson, Andrew; Schlapbach, Luregn J; Bielicki, Julia A; Trück, Johannes (2024). COVID-19 Vaccine Acceptance Among Parents of Children With Multisystem Inflammatory Syndrome in Children. The pediatric infectious disease journal, 43(4), pp. 361-364. Wolters Kluwer Health 10.1097/INF.0000000000004206

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Data on COVID-19 vaccine acceptability among parents of children with multisystem inflammatory syndrome (MIS-C) are limited. In this cohort of children with MIS-C, enrolled in the Swissped RECOVERY trial (NCT04826588), comparing intravenous immunoglobulins or methylprednisolone, who, in accordance with Swiss guidelines, were recommended for SARS-CoV-2 vaccination, 65% (73/112) of parents reported being vaccinated against SARS-CoV-2 before the MIS-C, while 70% were vaccinated after the MIS-C episode of their child. None of the children were vaccinated before the occurrence of the MIS-C, and only 9% (5/56) received the COVID-19 vaccine after the MIS-C. The predominant barriers to COVID-19 vaccination were concerns over potential side effects and insufficient support from their doctors. This emphasizes the crucial role of health care providers in promoting COVID-19 vaccination among children.

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