Kinematic analysis of a parallel mechanism for automated imaging of an Organ-on-a-Chip culture system

Schicklin, Cédric; Eugster, Manuela; Rauter, Georg; DuEPublico: Duisburg-Essen Publications Online, University Of Duisburg-Essen (2023). Kinematic analysis of a parallel mechanism for automated imaging of an Organ-on-a-Chip culture system. In: 9. IFToMM D-A-CH Konferenz. University of Duisburg-Essen, Germany 10.17185/duepublico/77403

Preview

Text IFToMM_DACH_2023_paper_22.pdf - Published Version Available under License Creative Commons: Attribution-Noncommercial (CC-BY-NC). Download (472kB) | Preview

Organ-on-a-Chip approach makes it possible to produce vascularized organoids for pre-clinical drug studies using incubators and rockers. Automation of organoids generation is desirable to reduce human resources and increase reproducibility. However, automation requires information such as the growth status of the organoids to be recorded directly within the incubator. Hereby, avoiding regular incubator opening by including an autonomous planar parallel robotic imaging system will prevent disturbing the organoids’ growth. To avoid rotations of the miniature microscope while inspecting the different organoids-on-a-chip in the constrained incubator space, the parallel robot is constrained to two translational DoFs. Here, we present the kinematic design of the robot that fulfils the workspace requirements and space constraints inside the incubator.

Interest & Impact

Downloads

26 since deposited on 26 Jan 2024
26 in the past 12 months

Citations

5 Citations in Web of Science ®
6 Citations in Scopus

Search

in Google Scholar™

Services

Actions (login required)

Edit item

Actions (login required)

Edit item