Eriks-Hoogland, Inge E; Barth, Michael A; Müller, Lorena L; Braun, Dominique; Curt, Armin; Arora, Mohit; Middleton, James W; Pannek, Jürgen (2024). COVID-19 and spinal cord injury: clinical presentation, clinical course, and clinical outcomes of people hospitalised. Spinal cord series and cases, 10(1), p. 5. Springer Nature 10.1038/s41394-024-00617-6
Full text not available from this repository. (Request a copy)STUDY DESIGN
Retrospective study OBJECTIVES: To describe the presenting symptoms/signs, clinical course and outcomes in hospitalised people with spinal cord injury (SCI) and symptomatic COVID-19 infections.
SETTING
One university hospital and two SCI centres in Switzerland.
METHODS
Descriptive analysis of symptoms/signs, clinical course and outcomes of people with SCI with symptomatic COVID-19 infections and need for hospitalisation.
RESULTS
Twenty-two people with SCI were included, 15 (68%) were male, median age 64.5 years (interquartile range, IQR, 52-73 years). Nine (41%) had tetraplegia, and eight (36%) were classified with motor-complete lesions. Frequent clinical symptoms were fever (59%), coughing (54%), fatigue (50%), and dyspnoea (27%). Most frequent complications were bacterial pulmonary superinfection (18%), and acute respiratory distress syndrome (18%). Fifteen persons (68%) needed oxygen therapy during the course of hospitalisation, and 7 (32%) people were ventilated. Median length of stay (LOS) was 23 days (IQR 15-35), varying by age for people under 60 years with a median LOS of 9 days (IQR 8-27), and for those older than 60 years with a median of 34 days (IQR 17-39), respectively. In total, 3 persons (14%) died during hospitalisation, all older with paraplegia.
CONCLUSIONS
Typical symptoms like fever and coughing were not present in all people. People with tetraplegia did not demonstrate worse outcomes, on the contrary, they had shorter LOS, no difference in ventilation needs, and no higher mortality compared to people with paraplegia. Older people showed longer LOS. This study recommends close supervision of the SCI population to detect early signs and symptoms of COVID-19 infection.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Department of Dermatology, Urology, Rheumatology, Nephrology, Osteoporosis (DURN) > Clinic of Urology |
UniBE Contributor: |
Pannek, Jürgen |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
2058-6124 |
Publisher: |
Springer Nature |
Language: |
English |
Submitter: |
Pubmed Import |
Date Deposited: |
14 Feb 2024 09:51 |
Last Modified: |
14 Feb 2024 09:51 |
Publisher DOI: |
10.1038/s41394-024-00617-6 |
PubMed ID: |
38351025 |
URI: |
https://boris.unibe.ch/id/eprint/192884 |
Actions (login required)
 |
Edit item |