Kasper, Burkhard S; Archer, John; Bernhardt, Boris C; Caciagli, Lorenzo; Cendes, Fernando; Chinvarun, Yotin; Concha, Luis; Federico, Paolo; Gaillard, William; Kobayashi, Eliane; Ogbole, Godwin; Vaudano, Anna Elisabetta; Wang, Irene; Wang, Shuang; Winston, Gavin P; Rampp, Stefan (2024). ILAE neuroimaging task force highlight: Subcortical laminar heterotopia. Epileptic Disorders, 26(2), pp. 225-232. Springer 10.1002/epd2.20206
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Epileptic_Disorders_-_2024_-_Kasper_-_ILAE_neuroimaging_task_force_highlight__Subcortical_laminar_heterotopia.pdf - Published Version Available under License Creative Commons: Attribution-Noncommercial-No Derivative Works (CC-BY-NC-ND). Download (1MB) | Preview |
The ILAE Neuroimaging Task Force publishes educational case reports that highlight basic aspects of neuroimaging in epilepsy consistent with the ILAE's educational mission. Subcortical laminar heterotopia, also known as subcortical band heterotopia (SBH) or "double cortex," is an intriguing and rare congenital malformation of cortical development. SBH lesions are part of a continuum best designated as agyria-pachygyria-band-spectrum. The malformation is associated with epilepsy that is often refractory, as well as variable degrees of developmental delay. Moreover, in an increasing proportion of cases, a distinct molecular-genetic background can be found. Diagnosing SBH can be a major challenge for many reasons, including more subtle lesions, and "non-classic" or unusual MRI-appearances. By presenting an illustrative case, we address the challenges and needs of diagnosing and treating SBH patients in epilepsy, especially the value of high-resolution imaging and specialized MRI-protocols.
Item Type: |
Journal Article (Original Article) |
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Division/Institute: |
04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Neurology |
UniBE Contributor: |
Caciagli, Lorenzo |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
1294-9361 |
Publisher: |
Springer |
Language: |
English |
Submitter: |
Pubmed Import |
Date Deposited: |
15 Feb 2024 09:50 |
Last Modified: |
13 Apr 2024 00:14 |
Publisher DOI: |
10.1002/epd2.20206 |
PubMed ID: |
38353525 |
Uncontrolled Keywords: |
double cortex epilepsy neuroimaging subcortical band heterotopia subcortical laminar heterotopia |
BORIS DOI: |
10.48350/192917 |
URI: |
https://boris.unibe.ch/id/eprint/192917 |
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