Cardiovascular disease as part of Long COVID: A systematic review.

Tsampasian, Vasiliki; Bäck, Maria; Bernardi, Marco; Cavarretta, Elena; Dębski, Maciej; Gati, Sabiha; Hansen, Dominique; Kränkel, Nicolle; Koskinas, Konstantinos; Niebauer, Josef; Spadafora, Luigi; Frias Vargas, Manuel; Biondi-Zoccai, Giuseppe; Vassiliou, Vassilios S (2024). Cardiovascular disease as part of Long COVID: A systematic review. (In Press). European journal of preventive cardiology SAGE Publications 10.1093/eurjpc/zwae070

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BACKGROUND

Long COVID syndrome has had a major impact on million patients' lives worldwide. The cardiovascular system is an important aspect of this multifaceted disease that may manifest in many ways. We have hereby performed a narrative review in order to identify the extent of the cardiovascular manifestations of the Long COVID syndrome.

METHODS AND RESULTS

An in-depth systematic search of the literature has been conducted for this narrative review. The systematic search of PubMed and Cochrane databases yielded 3,993, of which 629 underwent full text screening. A total of 78 studies were included in the final qualitative synthesis and data evaluation. The pathophysiology of the cardiovascular sequelae of Long COVID syndrome and the cardiac manifestations and complications of Long COVID syndrome are critically evaluated. In addition, potential cardiovascular risk factors are assessed, and preventive methods and treatment options are examined in this review.

CONCLUSIONS

This systematic review poignantly summarises the evidence from the available literature regarding the cardiovascular manifestations of Long COVID syndrome and reviews potential mechanistic pathways, diagnostic approaches, preventive measures and treatment options.

Item Type:

Journal Article (Review Article)

Division/Institute:

04 Faculty of Medicine > Department of Cardiovascular Disorders (DHGE) > Clinic of Cardiology

UniBE Contributor:

Koskinas, Konstantinos

Subjects:

600 Technology > 610 Medicine & health

ISSN:

2047-4873

Publisher:

SAGE Publications

Language:

English

Submitter:

Pubmed Import

Date Deposited:

22 Feb 2024 12:39

Last Modified:

23 Feb 2024 05:59

Publisher DOI:

10.1093/eurjpc/zwae070

PubMed ID:

38381595

BORIS DOI:

10.48350/193149

URI:

https://boris.unibe.ch/id/eprint/193149

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