Studer, M; Guggisberg, A; Gyger, N; Gutbrod, K; Henke, K; Heinemann, D (2024). Accelerated long-term forgetting in patients with acquired brain injury. Brain injury, 38(5), pp. 377-389. Informa Healthcare 10.1080/02699052.2024.2311349
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OBJECTIVE
Recent research suggests that patients with neurological disorders without overt seizures may also experience accelerated long-term forgetting (ALF). This term describes unimpaired learning and memory performance after standard retention intervals, but an excessive rate of forgetting over delays of days or weeks. The objective of this retrospective study was to investigate ALF in patients with an acquired brain injury (ABI) and to associate memory performance with executive functions.
METHODS
Verbal memory performance (short-term recall, 30-min recall, 1-week recall) was assessed in 34 adult patients with ABI and compared to a healthy control group (n = 54) using an auditory word learning and memory test.
RESULTS
Repeated measure analysis showed significant effects of time and group as well as interaction effects between time and group regarding recall and recognition performance. Patients with ABI had a significantly impaired 1-week recall and recognition performance compared to the healthy control group. Correlations between recall performance and executive functions were nonsignificant.
DISCUSSION
Our results demonstrate that non-epileptic patients with ABI, especially patients with frontal and fronto-temporal lesions, are prone to ALF. Additionally, our data support the assumption that ALF results from a consolidation impairment since verbal recall and recognition were impaired in patients with ABI.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Neurology 07 Faculty of Human Sciences > Institute of Psychology |
UniBE Contributor: |
Studer, Martina (A), Guggisberg, Adrian (A), Gyger, Naomi Rebecca, Gutbrod, Klemens, Henke, Katharina, Heinemann, Dörthe |
Subjects: |
600 Technology > 610 Medicine & health 100 Philosophy > 150 Psychology |
ISSN: |
0269-9052 |
Publisher: |
Informa Healthcare |
Language: |
English |
Submitter: |
Pubmed Import |
Date Deposited: |
04 Mar 2024 09:28 |
Last Modified: |
15 Mar 2024 00:15 |
Publisher DOI: |
10.1080/02699052.2024.2311349 |
PubMed ID: |
38385560 |
Uncontrolled Keywords: |
Acquired brain injury accelerated long-term forgetting delayed episodic memory recall executive functions memory consolidation |
BORIS DOI: |
10.48350/193184 |
URI: |
https://boris.unibe.ch/id/eprint/193184 |
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