VIRTOPSY: minimally invasive, imaging-guided virtual autopsy

Dirnhofer, Richard; Jackowski, Christian; Vock, Peter; Potter, Kimberlee; Thali, Michael J (2006). VIRTOPSY: minimally invasive, imaging-guided virtual autopsy. Radiographics, 26(5), pp. 1305-33. Easton, Pa.: Radiological Society of North America RSNA 10.1148/rg.265065001

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Invasive "body-opening" autopsy represents the traditional means of postmortem investigation in humans. However, modern cross-sectional imaging techniques can supplement and may even partially replace traditional autopsy. Computed tomography (CT) is the imaging modality of choice for two- and three-dimensional documentation and analysis of autopsy findings including fracture systems, pathologic gas collections (eg, air embolism, subcutaneous emphysema after trauma, hyperbaric trauma, decomposition effects), and gross tissue injury. Various postprocessing techniques can provide strong forensic evidence for use in legal proceedings. Magnetic resonance (MR) imaging has had a greater impact in demonstrating soft-tissue injury, organ trauma, and nontraumatic conditions. However, the differences in morphologic features and signal intensity characteristics seen at antemortem versus postmortem MR imaging have not yet been studied systematically. The documentation and analysis of postmortem findings with CT and MR imaging and postprocessing techniques ("virtopsy") is investigator independent, objective, and noninvasive and will lead to qualitative improvements in forensic pathologic investigation. Future applications of this approach include the assessment of morbidity and mortality in the general population and, perhaps, routine screening of bodies prior to burial.

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Journal Article (Further Contribution)


04 Faculty of Medicine > Service Sector > Institute of Legal Medicine > Management
04 Faculty of Medicine > Department of Radiology, Neuroradiology and Nuclear Medicine (DRNN) > Institute of Diagnostic, Interventional and Paediatric Radiology
04 Faculty of Medicine > Service Sector > Institute of Legal Medicine

UniBE Contributor:

Jackowski, Christian, Vock, Peter, Thali, Michael






Radiological Society of North America RSNA




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Date Deposited:

04 Oct 2013 14:47

Last Modified:

05 Dec 2022 14:14

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URI: (FactScience: 1867)

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