Tschopp, Samuel; Borner, Urs; Caversaccio, Marco; Tschopp, Kurt (2024). Long-term night-to-night variability of sleep-disordered breathing using a radar-based home sleep apnea test: a prospective cohort study. (In Press). Journal of clinical sleep medicine American Academy of Sleep Medicine 10.5664/jcsm.11070
Full text not available from this repository. (Request a copy)STUDY OBJECTIVES
Night-to-night variability of sleep-disordered breathing (SDB) limits the diagnostic accuracy of a single measurement. Multiple recordings using a reliable, affordable method could reduce the uncertainty and avoid misdiagnosis, which could be possible with radar-based home sleep apnea testing (HSAT).
METHODS
We recruited consecutive patients with suspected SDB and performed contactless radar-based HSAT with automated scoring (Sleepiz One) over ten nights. During the first night, patients were simultaneously measured with peripheral-arterial tonometry.
RESULTS
Twenty-four of the 28 included patients could achieve a minimum of four measurements. The failure rate was 16% (201 of 238 measurements). The apnea-hypopnea index (AHI) and oxygen desaturation index were consistently lower with radar-based HSAT compared to peripheral arterial tonometry. The variability of the AHI was considerable, with a standard error of measurement of 5.2/h (95%CI 4.6-5.7/h) and a minimal detectable difference of 14.4/h (95%CI 12.7-15.9/h). Alcohol consumption partially accounted for the variability, with an AHI increase of 1.7/h (95%CI 0.6-2.8/h) for each standard drink. Based on a single measurement, 17% of patients were misdiagnosed, and 32% were misclassified for SDB severity. After five measurements, the mean AHI of the measured nights stabilized with no evidence of substantial changes with additional measurements.
CONCLUSIONS
Night-to-night variability is considerable and stable over ten nights. HSAT using radar-based methods over multiple nights is feasible and well tolerated by patients. It could offer lower costs and allow for multiple-night testing to increase accuracy. However, validation and reducing the failure rate are necessary for implementation in the clinical routine.
CLINICAL TRIAL REGISTRATION
"Recording of Multiple Nights Using a New Contactless Device (Sleepiz One Connect) in Obstructive Sleep Apnea", ClinicalTrials.gov, NCT05134402.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Ear, Nose and Throat Disorders (ENT) |
UniBE Contributor: |
Tschopp, Samuel, Borner, Urs, Caversaccio, Marco |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
1550-9397 |
Publisher: |
American Academy of Sleep Medicine |
Language: |
English |
Submitter: |
Pubmed Import |
Date Deposited: |
19 Mar 2024 13:00 |
Last Modified: |
19 Mar 2024 13:00 |
Publisher DOI: |
10.5664/jcsm.11070 |
PubMed ID: |
38415722 |
Uncontrolled Keywords: |
Sleepiz WatchPAT diagnosis home sleep apnea testing night-to-night variability obstructive sleep apnea peripheral arterial tonometry sleep-disordered breathing |
URI: |
https://boris.unibe.ch/id/eprint/193606 |
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