Komninou, Maria Angeliki; Seiler, Theo G; Enzmann, Volker (2024). Corneal biomechanics and diagnostics: a review. International ophthalmology, 44(132) Springer 10.1007/s10792-024-03057-1
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PURPOSE
Corneal biomechanics is an emerging field and the interest into physical and biological interrelations in the anterior part of the eye has significantly increased during the past years. There are many factors that determine corneal biomechanics such as hormonal fluctuations, hydration and environmental factors. Other factors that can affect the corneas are the age, the intraocular pressure and the central corneal thickness. The purpose of this review is to evaluate the factors affecting corneal biomechanics and the recent advancements in non-destructive, in vivo measurement techniques for early detection and improved management of corneal diseases.
METHODS
Until recently, corneal biomechanics could not be directly assessed in humans and were instead inferred from geometrical cornea analysis and ex vivo biomechanical testing. The current research has made strides in studying and creating non-destructive and contactless techniques to measure the biomechanical properties of the cornea in vivo.
RESULTS
Research has indicated that altered corneal biomechanics contribute to diseases such as keratoconus and glaucoma. The identification of pathological corneas through the new measurement techniques is imperative for preventing postoperative complications.
CONCLUSIONS
Identification of pathological corneas is crucial for the prevention of postoperative complications. Therefore, a better understanding of corneal biomechanics will lead to earlier diagnosis of ectatic disorders, improve current refractive surgeries and allow for a better postoperative treatment.
Item Type: |
Journal Article (Review Article) |
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Division/Institute: |
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > Forschungsbereich Augenklinik > Forschungsgruppe Augenheilkunde 04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Ophthalmology |
UniBE Contributor: |
Komninou, Maria Angeliki, Seiler, Günter Theodor Michael, Enzmann, Volker |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
0165-5701 |
Publisher: |
Springer |
Language: |
English |
Submitter: |
Pubmed Import |
Date Deposited: |
14 Mar 2024 08:27 |
Last Modified: |
14 Mar 2024 08:36 |
Publisher DOI: |
10.1007/s10792-024-03057-1 |
PubMed ID: |
38478103 |
Uncontrolled Keywords: |
Biomechanical properties Biomechanics Brillouin spectroscopy Cornea |
BORIS DOI: |
10.48350/194237 |
URI: |
https://boris.unibe.ch/id/eprint/194237 |
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