Reducing the global burden of cerebral venous thrombosis: an international research agenda.

Coutinho, Jonathan M; van de Munckhof, Anita; Aguiar de Sousa, Diana; Poli, Sven; Aaron, Sanjith; Arauz-Góngora, Antonio; Conforto, Adriana; Krzywicka, Katarzyna; Hiltunen, Sini; Lindgren, Erik; Sanchez van Kammen, Mayte; Shu, Liqi; Bakchoul, Tamam; Belder, Rosalie; van den Berg, Rene; Boumans, Elisheva; Cannegieter, Suzanne; Cano-Nigenda, Vanessa; Field, Thalia Shoshana; Fragata, Isabel; ... (2024). Reducing the global burden of cerebral venous thrombosis: an international research agenda. International journal of stroke, 19(6), pp. 599-610. SAGE 10.1177/17474930241242266

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BACKGROUND

Due to the rarity of cerebral venous thrombosis (CVT), performing high-quality scientific research in this field is challenging. Providing answers to unresolved research questions will improve prevention, diagnosis, and treatment, and ultimately translate to a better outcome of patients with CVT. We present an international research agenda, in which the most important research questions in the field of CVT are prioritized.

AIMS

This research agenda has three distinct goals: (1) To provide inspiration and focus to research on CVT for the coming years; (2) To reinforce international collaboration; and (3) To facilitate the acquisition of research funding.

SUMMARY OF REVIEW

This international research agenda is the result of a research summit organized by the International Cerebral Venous Thrombosis Consortium in Amsterdam, the Netherlands in June 2023. The summit brought together 45 participants from 15 countries including clinical researchers from various disciplines, patients who previously suffered from CVT, and delegates from industry and non-profit funding organizations. The research agenda is categorized into six pre-specified themes: (1) Epidemiology and clinical features; (2) Life after CVT; (3) Neuroimaging and diagnosis; (4) Pathophysiology; (5) Medical treatment; and (6) Endovascular Treatment. For each theme, we present two to four research questions, followed by a brief substantiation per question. The research questions were prioritized by the participants of the summit through consensus discussion.

CONCLUSIONS

This international research agenda provides an overview of the most burning research questions on CVT. Answering these questions will advance our understanding and management of CVT, which will ultimately lead to improved outcomes for CVT patients worldwide.

Item Type:	Journal Article (Review Article)
Division/Institute:	04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Neurology
UniBE Contributor:	Heldner, Mirjam Rachel, Arnold, Marcel
Subjects:	600 Technology > 610 Medicine & health
ISSN:	1747-4949
Publisher:	SAGE
Language:	English
Submitter:	Pubmed Import
Date Deposited:	27 Mar 2024 14:48
Last Modified:	02 Aug 2024 00:12
Publisher DOI:	10.1177/17474930241242266
PubMed ID:	38494462
Uncontrolled Keywords:	CVT Cerebral venous thrombosis Epidemiology International Neuroimaging Pathophysiology Research agenda Stroke subtypes Summit Treatment
URI:	https://boris.unibe.ch/id/eprint/194423