Bleiziffer, Sabine; Appleby, Clare; Delgado, Victoria; Eltchaninoff, Helene; Gebhard, Catherine; Hengstenberg, Christian; Wojakowski, Wojtek; Petersen, Nathan; Kurucova, Jana; Bramlage, Peter; Rudolph, Tanja K (2024). Patterns of aortic valve replacement in Europe and adoption by sex. (In Press). International journal of cardiology(131996), p. 131996. Elsevier 10.1016/j.ijcard.2024.131996
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OBJECTIVE
Management of patients with severe aortic stenosis (AS) may differ according to the patient sex. This study aimed to describe patterns of aortic valve replacement (AVR) for severe AS across Europe, including stratification by sex.
METHODS
Procedure volume data for surgical aortic valve replacement (SAVR) and transcatheter aortic valve implantation (TAVI) for six years (2015-2020) were extracted from national databases for Austria, Czech Republic, Denmark, England, Finland, France, Germany, Norway, Poland, Spain, Sweden, and Switzerland and stratified by sex. Patients per million population (PPM) undergoing AVR per year were calculated using population estimates from Eurostat.
RESULTS
Between 2015 and 2019, AVR procedures grew at an average annual rate of 3.9%. In 2020, the average total PPM undergoing AVR across all countries was 339, with 51% of procedures being TAVI and 49% SAVR. AVR PPM varied widely between countries, with the highest and lowest in Germany and Poland, respectively. The average total PPM was higher for men than women (423 vs. 258), but a higher proportion of women (62%) than men (44%) received TAVI. The proportion of TAVI among total AVR procedures increased with age, with an overall average of 96% of men and 98% of women aged ≥85 years receiving TAVI; however, adoption of TAVI varied by country.
CONCLUSIONS
The analysis of temporal trends in the adoption of TAVI vs. SAVR across Europe showed significant variations. Despite the higher use of TAVI vs. SAVR in women, overall rates of AV intervention in women were lower compared to men.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Department of Cardiovascular Disorders (DHGE) > Clinic of Cardiology |
UniBE Contributor: |
Gebhard, Cathérine Simone |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
0167-5273 |
Publisher: |
Elsevier |
Language: |
English |
Submitter: |
Pubmed Import |
Date Deposited: |
02 Apr 2024 14:46 |
Last Modified: |
03 Apr 2024 00:17 |
Publisher DOI: |
10.1016/j.ijcard.2024.131996 |
PubMed ID: |
38555056 |
Uncontrolled Keywords: |
Aortic valve replacement Europe Sex Transcatheter aortic valve implantation |
BORIS DOI: |
10.48350/195439 |
URI: |
https://boris.unibe.ch/id/eprint/195439 |
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