Valvular heart disease: from mechanisms to management.

Praz, Fabien; Beyersdorf, Friedhelm; Haugaa, Kristina; Prendergast, Bernard (2024). Valvular heart disease: from mechanisms to management. The lancet, 403(10436), pp. 1576-1589. Elsevier 10.1016/S0140-6736(23)02755-1

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Valvular heart disease is common and its prevalence is rapidly increasing worldwide. Effective medical therapies are insufficient and treatment was historically limited to the surgical techniques of valve repair or replacement, resulting in systematic underprovision of care to older patients and those with substantial comorbidities, frailty, or left ventricular dysfunction. Advances in imaging and surgical techniques over the past 20 years have transformed the management of valvular heart disease. Better understanding of the mechanisms and causes of disease and an increasingly extensive and robust evidence base provide a platform for the delivery of individualised treatment by multidisciplinary heart teams working within networks of diagnostic facilities and specialist heart valve centres. In this Series paper, we aim to provide an overview of the current and future management of valvular heart disease and propose treatment approaches based on an understanding of the underlying pathophysiology and the application of multidisciplinary treatment strategies to individual patients.

Item Type:

Journal Article (Review Article)

Division/Institute:

04 Faculty of Medicine > Department of Cardiovascular Disorders (DHGE) > Clinic of Cardiology

UniBE Contributor:

Praz, Fabien Daniel

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1474-547X

Publisher:

Elsevier

Language:

English

Submitter:

Pubmed Import

Date Deposited:

03 Apr 2024 14:44

Last Modified:

22 Apr 2024 00:16

Publisher DOI:

10.1016/S0140-6736(23)02755-1

PubMed ID:

38554728

BORIS DOI:

10.48350/195441

URI:

https://boris.unibe.ch/id/eprint/195441

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