Panos, Leonidas D; Bargiotas, Panagiotis; Arnold, Marcel; Hadjigeorgiou, Georgios; Panos, Georgios D (2024). Revolutionizing Stroke Recovery: Unveiling the Promise of Stem Cell Therapy. Drug design, development and therapy, 18, pp. 991-1006. Dovepress 10.2147/DDDT.S460998
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Stem cells, renowned for their unique regenerative capabilities, present significant hope in treating stroke, a major cause of disability globally. This review offers a detailed analysis of stem cell applications in stroke (ischemic and hemorrhagic) recovery. It examines therapies based on autologous (patient-derived), allogeneic (donor-derived), and Granulocyte-Colony Stimulating Factor (G-CSF) based stem cells, focusing on cell types such as Mesenchymal Stem/Stromal Cells (MSCs), Bone Marrow Mononuclear Stem Cells (BMMSCs), and Neural Stem/Progenitor Cells (NSCs). The paper compiles clinical trial data to evaluate their effectiveness and safety and addresses the ethical concerns of these innovative treatments. By explaining the mechanisms of stem cell-induced neurological repair, this review underscores stem cells' potential in revolutionizing stroke rehabilitation and suggests avenues for future research.
Item Type: |
Journal Article (Review Article) |
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Division/Institute: |
04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Neurology |
UniBE Contributor: |
Panos, Leonidas, Arnold, Marcel |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
1177-8881 |
Publisher: |
Dovepress |
Language: |
English |
Submitter: |
Pubmed Import |
Date Deposited: |
03 Apr 2024 15:33 |
Last Modified: |
15 Apr 2024 14:51 |
Publisher DOI: |
10.2147/DDDT.S460998 |
PubMed ID: |
38567255 |
Uncontrolled Keywords: |
allogeneic stem cells transplantation autologous stem cells transplantation brain hemorrhage granulocyte-colony stimulating factor stem cell therapy stroke |
BORIS DOI: |
10.48350/195635 |
URI: |
https://boris.unibe.ch/id/eprint/195635 |
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