High numbers of DC-SIGN+ dendritic cells in lesional skin of cutaneous T-cell lymphoma

Schlapbach, Christoph; Ochsenbein, André; Kaelin, Ursula; Hassan, Akmal S; Hunger, Robert E; Yawalkar, Nikhil (2010). High numbers of DC-SIGN+ dendritic cells in lesional skin of cutaneous T-cell lymphoma. Journal of the American Academy of Dermatology, 62(6), pp. 995-1004. New York, N.Y.: Elsevier 10.1016/j.jaad.2009.06.082

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The role of dendritic cells (DCs) in disease progression of primary cutaneous T-cell lymphoma (CTCL) is not well understood. With their unique ability to induce primary immune responses as well as immunotolerance, DCs play a critical role in mediation of anti-tumor immune responses. Tumor-infiltrating DCs have been determined to represent important prognostic factors in a variety of human tumors.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Dermatology, Urology, Rheumatology, Nephrology, Osteoporosis (DURN) > Clinic of Dermatology
04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Medical Oncology

UniBE Contributor:

Schlapbach, Christoph; Ochsenbein, Adrian; Hunger, Robert and Yawalkar, Nikhil

ISSN:

0190-9622

Publisher:

Elsevier

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:07

Last Modified:

06 Dec 2013 13:19

Publisher DOI:

10.1016/j.jaad.2009.06.082

PubMed ID:

20466174

Web of Science ID:

000277940300013

URI:

https://boris.unibe.ch/id/eprint/196 (FactScience: 196879)

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