Sarbu, Adela; Guler, Sabina A (2024). [Interstitial Lung Disease associated with Connective Tissue Diseases]. Therapeutische Umschau, 81(1), pp. 4-11. Huber
Full text not available from this repository. (Request a copy)Interstitial Lung Disease associated with Connective Tissue Diseases Abstract: Interstitial lung diseases (ILD) are in up to one-third of cases associated with connective tissue diseases (CTD). In systemic sclerosis, rheumatoid arthritis, polymyositis/dermatomyositis, Sjögren's syndrome, and mixed connective tissue disease, an associated ILD significantly increases morbidity and mortality. The diagnostic workup for suspected CTD-ILD includes a range of functional, radiological, laboratory, and, if necessary, invasive tests. A thorough medical history and physical examination with targeted rheumatological diagnosis is particularly important. Also, patients with unclassified ILDs should be evaluated thoroughly for any underlying CTD. Pharmacological treatment options for CTD-ILD differ significantly from those for other ILDs. In addition to short-term glucocorticoids, antimetabolites and biological agents are often used. Antifibrotic drugs have also been successfully used in CTD-ILDs. The decision on whether and which immunosuppressive and/or antifibrotic therapy is indicated depends on the underlying disease, disease activity, extrapulmonary manifestations, severity of organ involvement, ILD progression, comorbidities, and patient preferences. Complex treatment decisions are ideally made in multidisciplinary expert teams.
Item Type: |
Journal Article (Review Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Department of Dermatology, Urology, Rheumatology, Nephrology, Osteoporosis (DURN) > Clinic of Rheumatology and Immunology |
UniBE Contributor: |
Sarbu, Adela-Cristina, Guler, Sabina Anna |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
0040-5930 |
Publisher: |
Huber |
Language: |
German |
Submitter: |
Pubmed Import |
Date Deposited: |
01 May 2024 16:05 |
Last Modified: |
01 May 2024 16:05 |
PubMed ID: |
38655827 |
URI: |
https://boris.unibe.ch/id/eprint/196210 |
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