Khalil, Maria; Lau, Hui Chong; Thackeray, James T; Mikail, Nidaa; Gebhard, Catherine; Quyyumi, Arshed A; Bengel, Frank M; Bremner, J Douglas; Vaccarino, Viola; Tawakol, Ahmed; Osborne, Michael T (2024). Heart-brain axis: pushing the boundaries of cardiovascular molecular imaging. Journal of nuclear cardiology, 36(101870), p. 101870. Springer 10.1016/j.nuclcard.2024.101870
Full text not available from this repository. (Request a copy)Despite decades of research, the heart-brain axis continues to challenge investigators seeking to unravel its complex pathobiology. Strong epidemiologic evidence supports a link by which insult or injury to one of the organs increases the risk of pathology in the other. The putative pathways have important differences between sexes and include alterations in autonomic function, metabolism, inflammation, and neurohormonal mechanisms that participate in crosstalk between the heart and brain and contribute to vascular changes, the development of shared risk factors, and oxidative stress. Recently, given its unique ability to characterize biological processes in multiple tissues simultaneously, molecular imaging has yielded important insights into the interplay of these organ systems under conditions of stress and disease. Yet, additional research is needed to probe further into the mechanisms underlying the heart-brain axis and to evaluate the impact of targeted interventions.
Item Type: |
Journal Article (Review Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Department of Cardiovascular Disorders (DHGE) > Clinic of Cardiology |
UniBE Contributor: |
Gebhard, Cathérine Simone |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
1532-6551 |
Publisher: |
Springer |
Language: |
English |
Submitter: |
Pubmed Import |
Date Deposited: |
30 Apr 2024 15:37 |
Last Modified: |
18 Jun 2024 00:14 |
Publisher DOI: |
10.1016/j.nuclcard.2024.101870 |
PubMed ID: |
38685398 |
URI: |
https://boris.unibe.ch/id/eprint/196399 |
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