Fujisawa, Miwako (2024). [Sarcoid Peripheral Neuropathy and Myopathy: A Diagnostic and Therapeutic Challenge]. Brain and nerve = Shinkei kenkyu no shinpo, 76(5), pp. 598-604. 10.11477/mf.1416202649
Full text not available from this repository. (Request a copy)Sarcoidosis is an idiopathic granulomatous multi-organ disease, primarily affecting the respiratory system, eyes, and skin, with less involvement in peripheral neurons and muscles. Sarcoid peripheral neuropathy encompasses cranial and spinal nerve impairment. Muscle involvement is often asymptomatic and revealed through imaging. Symptomatic muscle involvement is categorized into three clinical types: nodular myopathy, acute myopathy, and chronic myopathy. The identification of noncaseating granulomas in peripheral nerves or muscles, coupled with the exclusion of other diseases, is essential for establishing a definitive diagnosis of sarcoid peripheral neuropathy and myopathy. Sarcoid neuropathy and myopathy are typically managed with high-dose corticosteroids, immunosuppressants, or a combination of both. In recent times, the use of TNF-alpha inhibitors has notably increased. However, these conditions often exhibit resistance to treatment and may necessitate prolonged therapeutic interventions. Therefore, comprehensive examinations should be conducted before considering immunotherapy. Due to the rarity of these conditions, research on manifestation-specific treatments is lacking, and standard treatments for sarcoid neuropathy and myopathy have not been established. Additional treatment options for sarcoid neuropathy and myopathy are expected to become available in the future.
Item Type: |
Journal Article (Review Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Pre-clinic Human Medicine > Theodor Kocher Institute |
UniBE Contributor: |
Fujisawa, Miwako |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
1881-6096 |
Language: |
English |
Submitter: |
Pubmed Import |
Date Deposited: |
15 May 2024 09:46 |
Last Modified: |
15 May 2024 09:46 |
Publisher DOI: |
10.11477/mf.1416202649 |
PubMed ID: |
38741502 |
URI: |
https://boris.unibe.ch/id/eprint/196772 |
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