Laue, Jessica; Ambühl, Johanna; Surbek, Daniel (2024). Hybrid cord blood banking in a private-public-partnership: Women's perspectives. Transfusion, 64(7), pp. 1270-1278. Wiley-Blackwell 10.1111/trf.17858
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BACKGROUND
The increasing demand for umbilical cord blood (UCB) used in stem cell transplantation led to the establishment of cord blood (CB) banks worldwide. These include public foreign donor banks and private family-directed donor banks. Recently, our department has introduced a third banking model within a private-public-partnership. This hybrid banking allows for storage of family-directed CB units, while also getting Human leukocyte antigen (HLA)-typed and included in the national stem cell donor registry. So if the need arises, the HLA-compatible CB unit can be released to an unrelated recipient as a foreign donor stem cell graft.
OBJECTIVES
The aim of this study was to evaluate women's perspectives on the different CB banking options as well as retrospective satisfaction with their decisions.
METHODS
We performed a prospective survey study in postpartum women, using a validated questionnaire.
RESULTS
A total of 157 women were included in this survey study; 68% of them decided to have their UCB stored or donated. Among those women, 25% of them opted for hybrid storage, 72% of respondents stored UCB publicly, and 3% decided for private family-directed storage.
CONCLUSIONS
Our study shows the potential of hybrid banking as an attractive UCB storage option, as an alternative to family-directed banking rather than a substitute for public donation. Hybrid storage potentially combines advantages of family-directed banking as well as unrelated CB donation expanding the number of registered CB units available for transplantation and giving every pregnant woman the possibility to store UCB.
Item Type: |
Journal Article (Original Article) |
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Division/Institute: |
04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Gynaecology |
UniBE Contributor: |
Laue, Jessica, Surbek, Daniel |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
0041-1132 |
Publisher: |
Wiley-Blackwell |
Language: |
English |
Submitter: |
Pubmed Import |
Date Deposited: |
15 May 2024 16:00 |
Last Modified: |
17 Jul 2024 00:14 |
Publisher DOI: |
10.1111/trf.17858 |
PubMed ID: |
38746954 |
Uncontrolled Keywords: |
hybrid umbilical cord blood banking umbilical cord blood banking umbilical cord blood stem cell transplantation |
BORIS DOI: |
10.48350/196795 |
URI: |
https://boris.unibe.ch/id/eprint/196795 |
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