The great tit HapMap project: A continental-scale analysis of genomic variation in a songbird.

Spurgin, Lewis G; Bosse, Mirte; Adriaensen, Frank; Albayrak, Tamer; Barboutis, Christos; Belda, Eduardo; Bushuev, Andrey; Cecere, Jacopo G; Charmantier, Anne; Cichon, Mariusz; Dingemanse, Niels J; Doligez, Blandine; Eeva, Tapio; Erikstad, Kjell Einar; Fedorov, Vyacheslav; Griggio, Matteo; Heylen, Dieter; Hille, Sabine; Hinde, Camilla A; Ivankina, Elena; ... (2024). The great tit HapMap project: A continental-scale analysis of genomic variation in a songbird. Molecular ecology resources, 24(5), e13969. Wiley 10.1111/1755-0998.13969

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A major aim of evolutionary biology is to understand why patterns of genomic diversity vary within taxa and space. Large-scale genomic studies of widespread species are useful for studying how environment and demography shape patterns of genomic divergence. Here, we describe one of the most geographically comprehensive surveys of genomic variation in a wild vertebrate to date; the great tit (Parus major) HapMap project. We screened ca 500,000 SNP markers across 647 individuals from 29 populations, spanning ~30 degrees of latitude and 40 degrees of longitude - almost the entire geographical range of the European subspecies. Genome-wide variation was consistent with a recent colonisation across Europe from a South-East European refugium, with bottlenecks and reduced genetic diversity in island populations. Differentiation across the genome was highly heterogeneous, with clear 'islands of differentiation', even among populations with very low levels of genome-wide differentiation. Low local recombination rates were a strong predictor of high local genomic differentiation (FST), especially in island and peripheral mainland populations, suggesting that the interplay between genetic drift and recombination causes highly heterogeneous differentiation landscapes. We also detected genomic outlier regions that were confined to one or more peripheral great tit populations, probably as a result of recent directional selection at the species' range edges. Haplotype-based measures of selection were related to recombination rate, albeit less strongly, and highlighted population-specific sweeps that likely resulted from positive selection. Our study highlights how comprehensive screens of genomic variation in wild organisms can provide unique insights into spatio-temporal evolutionary dynamics.

Item Type:

Journal Article (Original Article)

Division/Institute:

08 Faculty of Science > Department of Biology > Institute of Ecology and Evolution (IEE) > Evolutionary Ecology

UniBE Contributor:

Richner, Heinz

Subjects:

500 Science > 570 Life sciences; biology

ISSN:

1755-0998

Publisher:

Wiley

Language:

English

Submitter:

Pubmed Import

Date Deposited:

16 May 2024 12:24

Last Modified:

04 Jun 2024 00:15

Publisher DOI:

10.1111/1755-0998.13969

PubMed ID:

38747336

Uncontrolled Keywords:

adaptation birds ecological genetics genomics/proteomics molecular evolution population genetics – empirical

BORIS DOI:

10.48350/196820

URI:

https://boris.unibe.ch/id/eprint/196820

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