Neurovascular Adverse Effects of Sars-Cov-2 Vaccination.

Panos, Leonidas D; Bargiotas, Panagiotis; Hadjigeorgiou, Georgios; Panos, Georgios D (2024). Neurovascular Adverse Effects of Sars-Cov-2 Vaccination. Drug design, development and therapy, 18, pp. 1891-1905. Dovepress 10.2147/DDDT.S464394

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The global deployment of SARS-CoV-2 vaccines has been pivotal in curbing the COVID-19 pandemic, reducing morbidity and mortality associated with the virus. While most of these vaccines have demonstrated high efficacy and overall safety, emerging reports have highlighted potential neurovascular adverse effects, albeit uncommon, associated with these vaccinations. This review aims to assess and summarize the current knowledge on the neurovascular complications arising post-SARS-CoV-2 vaccination. We conducted an extensive literature review, focusing on clinical studies and case reports to identify reported neurovascular events, such as ischemic stroke, cerebral sinus venous thrombosis, intracerebral hemorrhage, pituitary apoplexy and primary CNS angiitis Despite the relative rarity of these events, their impact on affected individuals underscores the importance of ongoing surveillance, early detection, and management strategies. We aim to provide healthcare professionals with the latest evidence on neurovascular adverse effects, facilitating informed decision-making in the context of SARS-CoV-2 vaccination programs. Furthermore, we highlight areas requiring further research to understand the pathophysiology of these adverse events better and to develop targeted prevention and treatment strategies.

Item Type:

Journal Article (Review Article)

Division/Institute:

04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Neurology

UniBE Contributor:

Panos, Leonidas

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1177-8881

Publisher:

Dovepress

Language:

English

Submitter:

Pubmed Import

Date Deposited:

06 Jun 2024 09:18

Last Modified:

07 Jun 2024 07:01

Publisher DOI:

10.2147/DDDT.S464394

PubMed ID:

38836116

Uncontrolled Keywords:

BNT162b2 COVID-19 ChAdOx1 NVX-CoV2373 SARS-CoV-2 coronavirus mRNA-1273 neurovascular adverse effects pandemic vaccines

BORIS DOI:

10.48350/197587

URI:

https://boris.unibe.ch/id/eprint/197587

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