[Microalbuminuria--a new cardiovascular risk factor?]

Eisenberger, U; Huynh-Do, U (2006). [Microalbuminuria--a new cardiovascular risk factor?]. Therapeutische Umschau, 63(9), pp. 565-8. Bern: Huber 10.1024/0040-5930.62.9.597

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Microalbuminuria is an established risk factor for renal disease, especially in the diabetic population. Recent studies have shown that microalbuminuria has also a highly relevant predictive value for cardiovascular morbidity and mortality. From normal to overt proteinuria levels, albuminuria shows a continuous marked increase in cardiovascular risk. This association is independent of other "classical" cardiovascular risk factors such as hypertension, hyperlipidemia or smoking. Furthermore it has a predictive value not only for patients with diabetic or renal disease, but also for hypertensive individuals or the general population. Angiotensin-converting enzyme inhibitors and angiotensin receptor blockers have been shown to display not only reno--but also cardioprotective effects. Their unique ability to lower albuminuria by 40% is related to a significant risk reduction in cardiovascular mortality. New clinical trials are needed to define "normal" albuminuria levels and how low we should go.

Item Type:

Journal Article (Further Contribution)

Division/Institute:

04 Faculty of Medicine > Department of Dermatology, Urology, Rheumatology, Nephrology, Osteoporosis (DURN) > Clinic of Nephrology and Hypertension

UniBE Contributor:

Eisenberger, Ute and Huynh-Do, Uyen

ISSN:

0040-5930

ISBN:

17048169

Publisher:

Huber

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:47

Last Modified:

06 Dec 2013 13:42

Publisher DOI:

10.1024/0040-5930.62.9.597

PubMed ID:

17048169

Web of Science ID:

000232107500004

URI:

https://boris.unibe.ch/id/eprint/19774 (FactScience: 2717)

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