Doesburg, Paul; Andersen, Jens-Otto; Scherr, Claudia; Kokornaczyk, Maria Olga; Baumgartner, Stephan (2024). Multidimensional Outcome Parameters in a Cress Seedling-CuCl2 Crystallization Assay to Corroborate Specific Effects of Stannum metallicum 30x Compared to Lactose 30x. (In Press). Homeopathy Thieme 10.1055/s-0044-1785517
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BACKGROUND
Previously we developed a test system which yielded highly significant evidence for specific effects of a Stannum metallicum 30x preparation in a multi-center replication trial. This test system is based on cress seed germination in homeopathic or control samples, CuCl2 crystallization of the cress extract, and subsequent digital textural image analysis of the resulting crystallization patterns.
OBJECTIVES
The current study aimed to investigate whether three novel outcome parameters could further corroborate and possibly characterize the specific effects of Stannum metallicum 30x.
METHODS
To this end, (1) cress seedling length, (2) a second texture analysis parameter, entropy and (3) the local connected fractal dimension (LCFD) of crystallization patterns as a measure of complexity were considered. The stability of the experimental setup was monitored throughout the entire investigation with systematic negative control (SNC) experiments.
RESULTS
Cress length and entropy revealed a time-modulated potency treatment effect, in the absence of a significant main treatment effect. This indicated that the effect of the potency treatment varied significantly across the different experimental days. LCFD yielded a highly significant potency treatment effect. In addition, a significant interaction of treatment with experimental day seems to indicate a modulation of this effect. No significant effects were observed in any of the evaluations of the SNC experiments, indicative of a stable experimental setup and a reliable and specific treatment effect. Neither significant nor strong correlations were found between the four parameters, indicating that they reflect different effects of Stannum metallicum 30x on the organism treated.
CONCLUSION
This quadruple characterization of the biological effects of Stannum metallicum 30x provides an unprecedented opportunity for basic homeopathy research into, among others, the presumed specificity of homeopathic preparations.
Item Type: |
Journal Article (Original Article) |
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Division/Institute: |
04 Faculty of Medicine > Medical Education > Institute of Complementary and Integrative Medicine (IKIM) |
UniBE Contributor: |
Kokornaczyk, Maria Olga, Baumgartner, Stephan |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
1476-4245 |
Publisher: |
Thieme |
Language: |
English |
Submitter: |
Pubmed Import |
Date Deposited: |
20 Jun 2024 12:44 |
Last Modified: |
22 Jun 2024 03:16 |
Publisher DOI: |
10.1055/s-0044-1785517 |
PubMed ID: |
38866048 |
BORIS DOI: |
10.48350/197799 |
URI: |
https://boris.unibe.ch/id/eprint/197799 |
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